That only very rarely happens. There's only a handful of people worldwide that have come forward expressing regret for transition, and most experience pressure from their religion to do so.
The primary use of this drug in adolescents and children is for precocious puberty, BTW.
That's 100% false. From the articles below:
There is no conclusive evidence that sex change operations improve the lives of transsexuals, with many people remaining severely distressed and even suicidal after the operation, according to a medical review conducted exclusively for Guardian Weekend tomorrow.
The review of more than 100 international medical studies of post-operative transsexuals by the University of Birmingham's aggressive research intelligence facility (Arif) found no robust scientific evidence that gender reassignment surgery is clinically effective.
Sex changes are not effective, say researchers
Persons with transsexualism,
after sex reassignment, have considerably higher risks for mortality, suicidal behaviour, and psychiatric morbidity than the general population.
Long-Term Follow-Up of Transsexual Persons Undergoing Sex Reassignment Surgery: Cohort Study in Sweden
Dr. McHugh, the author of six books and at least 125 peer-reviewed medical articles, made his remarks in a recent
commentary in the
Wall Street Journal, where he explained that transgender surgery is not the solution for people who suffer a “disorder of ‘assumption’” – the notion that their maleness or femaleness is different than what nature assigned to them biologically.
This intensely felt sense of being transgendered constitutes a mental disorder in two respects. The first is that the idea of sex misalignment is simply mistaken – it does not correspond with physical reality. The second is that it can lead to grim psychological outcomes.”
The transgendered person’s disorder,
said Dr. McHugh, is in the person’s “assumption” that they are different than the physical reality of their body, their maleness or femaleness, as assigned by nature. It is a disorder similar to a “dangerously thin” person suffering anorexia who looks in the mirror and thinks they are “overweight,” said McHugh.
Johns Hopkins Psychiatrist: Transgender is ‘Mental Disorder;' Sex Change ‘Biologically Impossible’
Mounting evidence over the last decade points to increased rates of autism spectrum disorders (ASD) and autism traits among children and adults with gender dysphoria, or incongruence between a person’s experienced or expressed gender and the gender assigned to them at birth. ASDs are characterized by difficulty with social interaction and communication as well as restricted, repetitive patterns of behavior. Approximately 1-2% of the population is estimated to meet criteria for ASDs, about twice higher in men than women.
The potential link between ASD and gender dysphoria was noted by researchers as early as
1981, when they noticed that 10% of 30 children with a clinical diagnosis of autism had trouble answering a gender identity question (“Are you a little boy or a little girl?”) that fewer than 1% of neurotypical children of the same age struggle with.
There's Growing Evidence For A Link Between Gender Dysphoria And Autism Spectrum Disorders
New research finds that transgender and gender-nonconforming youth are diagnosed with mental health conditions much more frequently than young people who identify with the gender they are assigned at birth.
Study: Transgender Youth More Likely To Be Diagnosed with Mental Disorders