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New study published in the journal Nature have shown that in some cases mRNA vaccines can lead to the formation of unwanted proteins. The scientists, however, reassure that no connection with side or negative effects has yet appeared, but during the development of future vaccines, it would be appropriate to correct this error.
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting - Nature
A study demonstrates that nucleotide modifications in mRNA-based therapeutics can lead to +1 ribosomal frameshifting during translation, yielding products that can trigger immune responses.
www.nature.com
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