probinson
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[/QUOTE]I mean, one could choose to post an opinion piece
This "opinion piece", published in the New England Journal of Medicine by a member of the FDA's vaccine advisory committee, is based on actual data. Here it is again, in red, in case you missed it.
On October 24, 2022, David Ho and colleagues released the results of a study examining levels of neutralizing antibodies against BA.4 and BA.5 after receipt of a monovalent or bivalent booster dose. They found “no significant difference in neutralization of any SARS-CoV-2 variant,” including BA.4 and BA.5, between the two groups.3 One day later, Dan Barouch and colleagues released the results of a similar study, finding that “BA.5 [neutralizing-antibody] titers were comparable following monovalent and bivalent mRNA boosters.” Barouch and colleagues also noted no appreciable differences in CD4+ or CD8+ T-cell responses between participants in the monovalent-booster group and those in the bivalent-booster group.4 Neither research group found the bivalent boosters to elicit superior immune responses. The results are now published in the Journal.
questioning how effective the boosters may or may not be, or one could post actual research results from the boosters in actual use : New Covid boosters work better against infection than previous shots, CDC finds
"Actual research results". **Processed to post article from NBC**
Are you serious? This links to this "study" by CDC's incomprehensibly incompetent propaganda wing of the CDC, MMWR (which I might add, is NOT peer-reviewed).
Effectiveness of Bivalent mRNA Vaccines in Preventing ..
This report describes the vaccine effectiveness of an updated ..
www.cdc.gov
The updated booster shots performed better in preventing infections in all adult age groups, with higher vaccine efficacy seen in people who waited longer before getting the updated booster, the CDC found.I wonder which approach is more likely to give an accurate representation of the reality on the ground?
The NEJM piece addresses this MMWR study by saying this.
On November 22, 2022, the CDC published data on the effectiveness of the BA.4 and BA.5 mRNA vaccines for preventing symptomatic infection within 2 months after receipt of the booster dose. For people who had received a monovalent vaccine 2 to 3 months earlier, the extra protection associated with the bivalent booster dose ranged from 28 to 31%. For those who had received a monovalent vaccine more than 8 months earlier, the extra protection ranged from 43 to 56%.5 Given the results of previous studies, it’s likely that this moderate increase in protection against probably generally mild disease will be short lived. As of November 15, 2022, only about 10% of the population for whom the bivalent vaccine had been recommended had received it.5 By December 2022, the BA.4 strain was no longer circulating, and BA.5 accounted for less than 25% of circulating SARS-CoV-2 strains, having been partially replaced by more immune-evasive strains, such as BQ.1, BQ.1.1, BF.7, XBB, and XBB.1.
The news cycle is turning against bivalent boosters for all.
Data Doesn’t Support New COVID-19 Booster Shots for Most, Says Expert
It’s time to rethink the blanket recommendation for giving the new Omicron booster to everyone
time.com
Younger, healthy people don't need another Covid booster, vaccine expert says, challenging FDA guidance
Protecting against Covid infection with the current mRNA technology is unrealistic, a vaccine expert said in a paper published in a major medical journal.
www.nbcnews.com
Interestingly, what Paul Offit is suggesting in all of this is already the recommendation in many countries. The US is an outlier in suggesting that 9-month old babies should be boosted with the bivalent booster. In most parts of the world, boosters are reserved for those who might actually derive some benefit from them (what a novel idea!)
The title of this thread attempts to implicate "science-deniers", but there is nothing more science-denying than suggesting six-month old babies require the same medical interventions as 85-year old adults.
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