I took ibprophin for a long period of time on my doctors orders, no less, and it ended up destroying my stomach, NOW i have to take zantac or prilosec every day of my life in order not to have horrible stomach pains, the doc had me taking it for arthritis pain and swelling. NOW, i get a monthly perscription for ten doses of lorcet, I only take it when i have my worst pain, and see the doc once a month to insure i ma not dependant on it, most months i dont use all of it. But, all OTC pain releivers now cause me great stomach pain. Not even two asprin for a headache is bareable now. And if i take an OTC pain reliever more than twice in the same day or two, i spit up blood... NOT FUN!