Yes, I will give you three examples:
1. The distribution of plants and animals. If the earth was flooded and recolonized 4,000 years ago from the single point where the ark landed, plants and animals would not be distributed the way they are today. There is no "single origin" point for the earth's biota, every continent (and every island, every river, every sea) is different and has its unique fauna and flora. In other words, you would need one ark for every island, continent, river, sea, ocean and even different sides of mountain ranges.
2. Genetic bottlenecks. Humans can sequence genomes now. We can calculate things like mutation rates. If all animal/plant populations had been reduced to single breeding pairs (or however few the Bible says there were) we would see a clear signal in every species population genetic structure. We do not see that. You can say that mutation rates are bogus, but even if they were, we would still see those genetic bottlenecks occurring in all species (albeit at different times). We do not see such thing.
3. Glaciers. If all the glaciers in the world today were submerged in water for months they would melt. Some of those glaciers (the ones in Antarctica for example) are more than 2 miles thick. It takes time, a long time for ice to accumulate like that. A global flood would wipe out all glaciers and we would only have very thin ones today. That is not the case.
Need more?