Hans Blaster
Hood was a loser.
- Mar 11, 2017
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Given the length and scope of your post I may respond is a couple posts. Let's start with this part:
You got close. You found a source we could use to estimate the cumulative population.
THere are about 150,000 Inuit. If we assume an average lifetime of ~70-75 years, about 2,000 people need to be born each year as replacement. If we assume a continuously fixed population size for 10,000 years we get 20,000,000 people.
With a cumulative population of 20 million and a instantaneous size of 150,000 how many adaptive mutations will be fixed in the population according to your model?
I have no idea of the number of Inuit that have ever lived. From Wikipedia:
Inuit - Wikipedia
There are Inuit populations in Europe, United States, Canada, Greenland, and related ethnic groups from Asia and who knows how many in the past and where. If there were a billion people in that lineage, that would be enough genome replications to give about 1 mutation at every site in the genome. Depending on when the adaptive mutation occurred, the frequency of that variant could increase over generations improving the probability of a recombination event with another parent with a different adaptive allele. As I estimated earlier, this lineage might accumulate 5-10 adaptive mutations for various selection conditions (diseases, diet, thermal stress, etc.) When it comes to creating new alleles, it is all about replication because that's when you have a possibility of a mutation occurring, some will be detrimental, some will be neutral, and on rare occasions, adaptive.
You got close. You found a source we could use to estimate the cumulative population.
THere are about 150,000 Inuit. If we assume an average lifetime of ~70-75 years, about 2,000 people need to be born each year as replacement. If we assume a continuously fixed population size for 10,000 years we get 20,000,000 people.
With a cumulative population of 20 million and a instantaneous size of 150,000 how many adaptive mutations will be fixed in the population according to your model?
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