Alan Kleinman
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- Feb 14, 2021
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Random mutations are a diverging (entropy increasing) process. Without natural selection, over time, genomes would consist of random sequences of bases. Are you saying that in that random mutation process can't produce a mutation that might improve the reproductive fitness of the particular variant in a particular environment? How and why do drug-resistant variants appear?I have a copy on my desk- 'The Origin of Species- by Means of Natural selection'
Then as now, you can select exactly nothing into existence - it is a destructive/ filtering process that leaves you with a smaller set of options than you began with. i.e. opposite of his tree of life.
That's true, but with each replication, the genetic apple can fall a little further from that tree than the previous apple, if natural selection allows it for the given environment.After the discovery of quantum mechanics- apples still fall from trees
and genetic apples will always fall not far from theirs
Are you claiming that you can't compute the divergence of a genetic sequence based on the knowledge of the mutation rate and the number of replications?The tempting mistake in both cases, is extrapolating a superficial observation into a comprehensive explanation.
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