Given that the reader of the text already knows that Isaac is the son of promise that God gave Abraham, because the whole point of Genesis is a prologue to the Exodus and the reader (or hearer) was a devout Israelite with an understanding of God's covenant promises already fulfilled, the whole point of the story is for teaching.
I believe on of the classical Jewish interpretations (I might be wrong or remembering incorrectly) is that the story is about God's rejection of human sacrifice; the point is therefore not to see if Abraham will do it or not, but in order to really emphasize God's non-acceptance of human sacrifices.
A Christian reading of the text has typically been read typologically, God providing in Isaac's stead as pointing to the event of the Cross.
But I suppose to answer the question in the OP, no I wouldn't destroy the universe. Just as I wouldn't kill or harm another individual. And more than likely if I start hearing voices telling me to do such things I would seek professional, medical help.
-CryptoLutheran
Except that the writer of Hebrews specifically says that Abraham expected God to bring Isaac back to life in order to make good on His promise. IOW, Abraham never believed he was making a true sacrifice...God would give Isaac back to him to make good on His promise.
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