Going with the supernatural theme here...
Maybe they're were all looking for an escape from something.
Jack - escape from his father's influence and the pressures of medicine.
Kate - escape from the consequences of her actions, prison.
Claire - escape from her stalker.
Locke - escape from the confines of his wheelchair.
Boone - escape from Shannon's hold on him.
Sawyer - escape from the pain of his childhood.
Sayid - escape from the guilt of the horrible things he's seen and done.
Sun - escape from her marriage and oppression.
Charlie - escape from everything.
LOL, I'm not sure what Jin, Michael, Walt, and Hurley could be trying to escape from.
Blah, blah, blah..I'm rambling...and probably not going anywhere with it.
Personally, I really can't wait to see Hurley's story. Any thoughts about him?