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ketamine

Quid est Veritas?

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Who is giving Ketamine to depressed people? It is an Anaesthetic drug, with analgesic properties. It causes a dissociative state and can cause vivid nightmares. Certainly inappropriate as a anti-depressant. It inactivates NMDA receptors, and releases noradrenalin stores (which it therefore depletes), but I don't see how that would be useful in depression.

Looking it up, I see they have done limited trials (the best evidence being only 18 people) that showed anti-depressant effects. That makes it a functionally untested treatment, with such limited and small scale testing, and Ketamine is a highly dangerous drug that has become associated with abuse and accidental death.
 
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well hey

little.soul
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Who is giving Ketamine to depressed people? It is an Anaesthetic drug, with analgesic properties. It causes a dissociative state and can cause vivid nightmares. Certainly inappropriate as a anti-depressant. It activates NMDA receptors, and releases noradrenalin stores (which it therefore depletes), but I don't see how that would be useful in depression.

Looking it up, I see they have done limited trials (the best evidence being only 18 people) that showed anti-depressant effects. That makes it a functionally untested treatment, with such limited and small scale testing, and Ketamine is a highly dangerous drug that has become associated with abuse and accidental death.
You know nothing about ketamine
 
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Quid est Veritas?

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You know nothing about ketamine
You are talking to an Anaesthetist. I have literally written tests about it, and use it every day of my life to Anaesthetise patients and for its analgesic properties.
 
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"Ketamine is a medication mainly used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain, sedation in intensive care, and depression." -wikipedia

..and heres an entire lecture on it:
 
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EstherRising

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Are any of you getting a prescription for ketamine? If so what did you find out about it? If you are already on it, what have the results been?
Hi! I have been receiving ketamine infusions for about 6 months now and I feel better than I have in many years. I have PMDD which presents itself as severe depression for 1/2 the month. I've tried every medication out there and none have worked. The infusions have been amazing for my overall well being. THey are not for the faint of heart, however, so now that I'm in the maintenance phase I plan to explore the lozenges or nasal. I haven't found them yet... Good luck!
 
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