If people really have had no opportunity to hear about God and his salvation, then they have had no opportunity to reject him either.
I believe that God is merciful and will not condemn someone for rejecting him, when in fact they were never told about him.
As stated in Psalm 19, and read in the book of Job, as described by Paul in Romans 1, and as Paul actually witnessed in Athens-- there is enough God visible in creation that any adult has all the information necessary to acknowledge His existence and grasp His essential virtuous nature. No adult has an excuse for not doing at least that much.
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