God has always taken the 'unwise' to confound the 'wise' (or those who think they are wise).
When God chose David, a thirteen year old boy, with no experience in battle, untrained in any way and a mere shepherd boy to fight the best fighter, a giant named Goliath, trained in battle and the 'best' that the other side had. He chose what would seem to be the worst choice to show His glory in that He can make even the most simplistic things grand.
In the same sense, Christ chose fishermen, uneducated at the bottom of society in terms of wealth or education or even influence to become His disciples and later apostles and build His church.
1 Corinthians 1:26-28
26 Brothers, consider the time of your calling: Not many of you were wise by human standards; not many were powerful; not many were of noble birth. 27
But God chose the foolish things of the world to shame the wise; God chose the weak things of the world to shame the strong. 28 He chose the lowly and despised things of the world, and the things that are not, to nullify the things that are,
This is a reoccuring theme, I have listed verses below:
Psalm 8:2
From the mouth of infants and nursing babes You have established strength Because of Your adversaries, To make the enemy and the revengeful cease.
Isaiah 44:25
Causing the omens of boasters to fail, Making fools out of diviners, Causing wise men to draw back And turning their knowledge into foolishness,
Jeremiah 8:9
"The wise men are put to shame, They are dismayed and caught; Behold, they have rejected the word of the LORD, And what kind of wisdom do they have?
1 Corinthians 1:20
Where is the wise man? Where is the scribe? Where is the philosopher of this age? Has not God made foolish the wisdom of the world?
1 Corinthians 1:21
For since in the wisdom of God, the world through its wisdom did not know Him, God was pleased through the foolishness of what was preached to save those who believe.
1 Corinthians 2:12
We have not received the spirit of the world, but the Spirit who is from God, that we may understand what God has freely given us.
James 2:5
Listen, my beloved brothers: Has not God chosen the poor of this world to be rich in faith and to inherit the kingdom He promised those who love Him?