So? No one said they were simple! ..
However, whole cell biochemical process models have already been developed .. ie: the tested knowledge is there.
Life-functional
artificial DNA has also been developed and tested in the lab.
Artificial functional ribozymes have also been created
Oh .. and the other key research on:
i) constraint closure in open non equilibrium systems, was done by Monteville and Mossio and;
ii) phase transitions of autocataytic sets, was done by Erdos And Renyl.
(Haven't got handy links/references to the above relevant papers/work, just yet).
Stuart Kauffman used (i) and (ii) above in his work on his Autocatalytic Set Abiogenesis Hypothesis , too.