I refuse to believe I'm the only Lost-fan in this place.
You aren't. I was quite disappointed by the finale and the way the "flash sideways" were explained, but that doesn't remove "Lost" from my all-time-favourites list.
So, here goes:
1) Lost (excellent characters, wonderful plots, great mysteries - and not so great solutions for the same, if any)
2) Battlestar Galactica (the re-imagined series, not the 1979 Star Wars-ripoff); I haven't finished that one yet, and I've heard the finale's not exactly gold, either, but that cannot spoil an otherwise excellent series: again, multi-faceted characters and plot lines abound.
3) Babylon 5: another series I never really finished, but definitely one that needs to be on this list on account of introducing extended plot lines spanning several seasons. The special effects look extremely cheesy in retrospect, but that cannot really distract from just how epic this series was.
4) Veronica Mars: she's got to have a place here, if only to detract from the fact that almost all series on this list are of the mystery/sci-fi kind. Brilliant dialogue, great characters, and the first season really excelled at building up a season-wide story arc.
5) Firefly: another one that got cancelled too soon. This series held lots of Whedonesque fun, and it was one of the few that actually insisted on not having sound effects in space. Lovely!
6) Twin Peaks: what can I say? I have a soft spot for the genius of David Lynch. Just because it's surreal doesn't mean that it doesn't make any sense.
7) Buffy the Vampire Slayer: hey, my screen name is an homage to one of the show's female lead characters , so you should have seen this one coming. I always liked this extended allegory on facing the horrors of the teenage years and coming of age.
8) Rome: now THAT was an excellent mini-series! Titus Pullo rules!
9) The X-Files: I didn't follow that series slavishly, but I was quite fond of it back in the 1990s.
10) The Simpsons: no list is complete without the yellow family. Great satire on the American way of life.