We're not talking about philosophical worldviews though. We are talking about actual hard science.
Science doesn't deal in truth or certainty. Here's a good explanation;
What Science Isn't, Part IV: Science isn't Truth and it isn't certainty
Some people assume that scientists have generated a body of knowledge that is sure to be true. Some ideas, after all, are known with enough certainty that most of us take them for granted. An example is our common assumption that the earth orbits the sun. Much scientific evidence supports that idea, which is the heliocentric theory of the solar system, and most of us take it as "true". However, no human has observed the solar system and seen the earth traveling in an orbit around the sun. It's just a theory, if a nearly inescapable one.
In that sense, most scientists will concede that, although they seek Truth, they don't know or generate Truth. They propose and test theories, knowing that future evidence may cause refinement, revision, or even rejection of today's theories. Ask a scientist about an issue that's not directly observable, and you probably hear an answer that starts with something like "The evidence suggests that . . ." or "Our current understanding is . . .". You're not hearing waffling or indecision. You're hearing a reasoned recognition that we can't know many things with absolute certainty - we only know the observable evidence. However, we can reach the best possible conclusion based on the most complete and modern evidence available.
That contrasts strongly with the knowledge claimed by many other people. Many people claim that they, or a book or books they endorse, hold all relevant knowledge and that such knowledge is absolutely and unquestionably true. The Bible, for example, is often held up as containing all knowledge, and as being literal and infallible Truth. No science book has ever been endorsed that way, nor should it ever be.
As an example, consider the question "How did the world begin?". A scientist's answer will begin with the evidence that we've gleaned from decades if not centuries of astronomical study, which includes several lines of evidence about the motions of galaxies. It will conclude with a theory that fits the accumulated evidence. There won't be, or at least oughtn't be, any statement about absolute truth.
In contrast, some other people will answer that the world was created by a certain deity a certain number of years ago. If asked about their level of certainty, these people generally respond that they have absolutely no uncertainty. No scientist thinking about what he or she is saying will answer with that degree of certainty, regardless of the evidence available to them, nor will they lay that kind of claim to Truth. They may have a high level of confidence if there's abundant evidence, but they won't claim absolute Truth or absolute certainty.
It's worth remembering that a person's admission of uncertainty doesn't mean they're wrong, whether the issue is in politics, economics, religion, or science. In fact, a person who admits some uncertainty in their thinking is often closer to the truth, or at least understands the issues better, than someone who claims absolute certainty. Shouting loudest does not generate truth.