I was miffed about how the character of Renee was treated. First, the vast majority of people with mental illnesses (including those with borderline personality disorder, which I think the psychiatrist Dr. Remus told Wilhelmina was Renee's diagnosis) are not homicidal pyromaniacs. Inclined to paranoia, yes. But most people with mental illnesses only intend to harm themselves if they physically harm anyone at all.
Second, Wilhelmina and Marc's changing Renee's medication should be exposed and punished ASAP. That is a modern-day variant of "gaslighting" (from the 1944 film Gaslight, in which a man tries to drive his wife into mental illness so that she enters a mental hospital and he gets her fortune) and should not be considered remotely funny.
Third, when Daniel told Betty that he loved Renee, it implied that his relationship with Renee was over. Although Renee set fire to his apartment, she was no more morally responsible for the deed than a child. Therefore, Daniel not only should have stayed by Renee, visiting her regularly in the mental hospital, but marry her. (I disapprove strongly of even fictional couples living together without marrying.) After all, Renee was taking her medication -- it was not her fault that it was the wrong medication. Besides, it would do some good to have a sympathetically portrayed major character with mental illness in a show like Ugly Betty.
On another subject, I like Henry, but he is too committed to Charlie and their child, even though their relationship is over. I would not want to be romantically involved with a man who is the father of another woman's (unborn) child. Betty should let Henry and Charlie go to Tucson and marry, and Betty should marry Gio.
when they first introduced him to the show, he had integrity -- complaining about fake "Mode girls" and encouraging Betty to follow her dreams. He even refused to make a sandwich with five sundried tomatoes (as opposed to three) because he thought they would overshadow the turkey! Lately it seems he's simply turned into a star-crossed lover. But I still think they've got the best chemistry. 
