pitabread
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- Jan 29, 2017
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Science asserts "C" but is silent about how these "." occur.
This isn't really true though. If you spend time reading scientific literature on how things evolved, there is a lot of work on reconstructing evolutionary pathways. This even includes things like recreating hypothetical ancestral genomes in order to study the required mutations to lead to particular outcomes.
Here's a specific example: https://www.scientificamerican.com/article/the-surprising-origins-of-evolutionary-complexity/
By comparing the differences in the genes for Vma3 and Vma11, Thornton and his colleagues reconstructed the ancestral gene from which they both evolved. They then used that DNA sequence to create a corresponding protein—in effect, resurrecting an 800-million-year-old protein. The scientists called this protein Anc.3-11—short for ancestor of Vma3 and Vma11. They wondered how the protein ring functioned with this ancestral protein. To find out, they inserted the gene for Anc.3-11 into the DNA of yeast. They also shut down its descendant genes, Vma3 and Vma11. Normally, shutting down the genes for the Vma3 and Vma11 proteins would be fatal because the yeast could no longer make their rings. But Thornton and his co-workers found that the yeast could survive with Anc.3-11 instead. It combined Anc.3-11 with Vma16 to make fully functional rings.
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