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Seroquel??

trustinhim83

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Anyone tried this? I am reading on some other forums that is makes you a walking zombie. Don't want that. I've read some other say it works quite well for them. It is supposed to help a lot with sleep, and also helps with depression.
Mood stabilizers are out of the question for me right now because we are planning a pregnancy soon. I'm not even sure if I'll take anything at all because of that, but still undecided. I really need some relief, so I'm trying to weigh that decision.
Seroquel has been mentioned to me by my psych. as a much safer option that he feels might work well for me.
I mainly suffer from mixed episodes, agitated/euphoric depression, and hypomania.
Also, have you tried Haldol, or Zyprexa either?
 
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I'm bipolar and I've taken Seroquel for about six years give or take. Long before it went generic. The problem is some people (like myself) have a sensitivity to it. If you have that sensitivity, the prescribed minimum dose is about five times what you need. I take a pediatric dose (50mg) and it knocks me out just fine every night, I get at least 8 hours restful sleep when ordinarily I'd get three.

If I try to get up before 8 hours is up I get the famous "Seroquel hangover" and it lasts all day. But all in all Seroquel was a godsend for me. I still consider it my most effective med for my bipolar.
 
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ChristianSambodhi

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I mainly suffer from mixed episodes, agitated/euphoric depression, and hypomania.

You sound like me. I've been on Seroquel twice. I liked it a lot. It helped stop the mixed episodes and the hypomania. My mind was clear. However, I did still have some problems with the depression and it gave me the munchies. I also had some troubles getting up on the morning (once I was up, I was fine) and it was hard for me sometimes to find words when I was talking (in other words, my mind was clouded). Now, I also have Fibromyalgia and didn't know this at the time I was taking the Seroquel; so maybe it was more "Fibro fog" than the meds.

All in all, I would try Seroquel again if I thought I could do better getting up in the morning and with the hunger.
 
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All in all, I would try Seroquel again if I thought I could do better getting up in the morning and with the hunger.

I gain weight with Seroquel too but I always attributed it to the fact that I was asleep for 5 extra hours instead of burning calories.
 
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ChristianSambodhi

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I gain weight with Seroquel too but I always attributed it to the fact that I was asleep for 5 extra hours instead of burning calories.

Fair enough. I actually was more alert once I got up and able to do more activities, so maybe that's why I felt munchie? These meds work with everyone differently and sometimes you can't tell what is causing what. It's frustrating, but an interesting puzzle at the same time.
 
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trustinhim83

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Christiansambodi, may I ask, what are you taking now instead? I have trouble finding words, or sometimes accidentally use the incorrect word when talking. I think this might simply a bipolar thing, even off meds.

Attributing the weight gain to sleeping extra sounds realistic. That would make sense. I've been reading that the weight gain is due to water retention as well. I am a little concerned about this, but not majorly. I am currently 5'7" and only 120lbs- slightly underweight. This is the most I've ever weighed in my life. During depressive episodes I usually drop down to about 115lbs in a matter of days because of loss of appetite. I'll be shocked and amazed if anything makes me actually gain any weight. However, I definitely don't want to get fat. At this point though I'll take thick and healthy over skinny and disturbed.

Did you all find you were able to function at your job ok, without making clumsey mistakes? Were you ok with working on detail while on the med?

Also, about how long did it take your body to adjust to Seroquel?
 
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ChristianSambodhi

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Christiansambodi, may I ask, what are you taking now instead? I have trouble finding words, or sometimes accidentally use the incorrect word when talking. I think this might simply a bipolar thing, even off meds.

Attributing the weight gain to sleeping extra sounds realistic. That would make sense. I've been reading that the weight gain is due to water retention as well. I am a little concerned about this, but not majorly. I am currently 5'7" and only 120lbs- slightly underweight. This is the most I've ever weighed in my life. During depressive episodes I usually drop down to about 115lbs in a matter of days because of loss of appetite. I'll be shocked and amazed if anything makes me actually gain any weight. However, I definitely don't want to get fat. At this point though I'll take thick and healthy over skinny and disturbed.

Did you all find you were able to function at your job ok, without making clumsey mistakes? Were you ok with working on detail while on the med?

Also, about how long did it take your body to adjust to Seroquel?

Sure! I am more than happy to share my experiences. I was recently taking Geodon but I had a really hard time eating. I was sick to my stomach for over a week and then I didn't want to eat anything for months, even after my stomach calmed down! I am also slightly underweight. However, Geodon and Seroquel helped me the most and I have been on almost everything.

In regards to my adjustment to Seroquel, I did adjust within a few days. Yes, I got a little sick at first (I always do); but the ONLY things that lingered were dry mouth, feeling munchie, having a hard time getting up, and the foggy mind. However, I was highly functional on Seroquel. I worked 20 hours a week and went to graduate school full-time. I made awesome grades and my work didn't really suffer (although I will admit I was late a couple of times because it was hard to get up). I was still able to express myself well in writing, which is the main thing I need to be able to do in my profession.

I am on day 4 of Abilify and it's making me sick too. I also take Lyrica for Fibro and I don't think the meds are playing well together (there aren't any serious interactions, just minor annoying ones). I have an awful headache and I am still so dizzy, I can't drive anywhere. I also don't feel right mentally, to a degree. This might go away when I go up to 5mg; but, if it doesn't, I am going to call the doctor. If Abilify doesn't work, I might try Seroquel again. I don't want to feel sick on the Geodon...

Meds work differently for every single person. What can make one person gain weight will make another person lose weight. The most weight neutral drug is Lamictal, followed by Geodon, Topamax, Trileptal, and Abilify. The main drug that has been known to cause weight gain is Depakote. I couldn't handle how ravenously hungry I felt on that drug; however, Seroquel was tolerable and, although I felt hungry, I didn't gain hardly any weight.

Bottom line: If your doctor thinks Seroquel might help, and you have insurance to pay for it, give it a try! It is a safer option, like your doc said, and I think it's worth a shot. You might want to look into Lamictal (which didn't give me many side effects at all) and Geodon (if you can tolerate it) as well. Like with the weight, meds can make one person feel like a zombie and another one feel absolutely nothing. It's always a bit of a gamble; but your doc knows how you have reacted to previous medications and can make a more educated guess than anyone else.
 
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trustinhim83

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Thanks both, for the replies!

ChristianSambodhi,
Thanks for the additional info! It sounds like Seroquel worked well for you from what you're describing. Why are you changing meds?

I am honestly very afraid of going on any med, but its my last resort, and know it's the right thing to do. I've been obsessing about weather to go on a med, and what med to take etc. I feel very paranoid about it. My doc is taking it slow with me, and still continuing evaluation. He mentioned Seroquel as a prime choice on last visit, and when I return next week for my third visit, I believe I will be given a prescription. It seems he would like to give me a mood stabilizer as well, but I cannot take any of them because my husband and I are planning for a baby this year. He said Lamictal (the safer mood stabilizer during pregnancy) wouldn't be the best choice for me, for whatever reason. I think he would prefer to put me on Lithium or Depakote, just not right now.

All feedback on Seroquel is much appreciated! I am nervous that I will be dysfunctional at work. In my job I work with my hands mainly, and have to use detail a lot. I am one on one with people, and I also have to manage my time very closely to be on time for appts.
I wonder if I'll need to take a week off from work to get adjusted to the med??? I'll talk this over with my doc. on next visit.
 
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ChristianSambodhi

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I am changing meds because I have a new psychiatrist and he wanted to try Abilify first. I am not 100% happy about it, but I am willing to give it a fair shot. Plus, I can't afford meds right now and Abilify will assist me with the cost. I don't know if AstraZeneca is harder to get help from or why the doctor insisted on Abilify. Sometimes doctors have their "go to" drugs and want to try those first.

I used to be afraid of meds; however, after being on almost every single one, I realized that they don't change who you are, they just take the edge off. Yes, some have nasty side effects, but you can always stop if the side effects become troublesome. Don't be afraid to insist on another medicine after a week or two if you don't find any change in the side effects and can't tolerate them.

Seroquel is safe and has helped many people. Who knows, you may be lucky and this med works and you won't have to switch! It's rare, but it happens. It sounds like your doc is doing what is best by taking things slow. I didn't tolerate Lithium well.

You shouldn't have to take a week off. You take Seroquel at night, so you would start on a Friday night and give yourself two days/nights to adjust. You might have to take Monday off depending on how you respond. Always bump up your meds on a Friday night so you can adjust over the weekend. My only concern is your mornings; but if you can get out of bed, shake it off (maybe grab a coffee or tea), you will be fine.

I'll be praying for you!
 
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trustinhim83

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I work four days on and three days off. So it sounds like those three days off will give me some time to adjust. I'll just start it after my last day of work before that, as you are suggesting.

Thanks a lot, everything you said is very encouraging. I'll pray for you as well as you're switching meds!
 
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trustinhim83

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Seroquel never helpd me sleep and it made me gain weight , so I had my pydoc take me off of it .

That's just great. Well, my options at this point pretty much are Seroquel, Haldol, & Zyprexa since we are in pre-conception planning mode. Seroquel is supposed to be the lowest risk, and also the one the doc. thinks will work best for me. Just talked to my aunt, who takes Depakote for Bipolar. My doc would also like me to take either that or Lithium at some point, but cannot do so now because they both cause birth defects. So my choices are very limited. I guess I'll just try the Seroquel if that ends up being what he prescribes after all, and see what happens. Will let you guys know how it works out.

Thanks for the input.
 
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ChristianSambodhi

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Depakote and Lithium , I could not take either , as the Seroquel goes give it a try , each drug works different on different people . It may be great for you .

I couldn't tolerate Depakote and I had a really bad reaction to Lithium (which I guess is rare). I agree with Loven, though, give it a try. I think it's a good first choice for people to try.

As for Abilify... I was fine yesterday, but feel sick again today. UGH! This is so frustrating.
 
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ChristianSambodhi

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There's something else I just thought of and this is for anyone starting medications for Bipolar. I've had several doctors tell me that Bipolar is hereditary and sometimes medications that help one member of the family will help another. The same goes for medications that respond negatively with the body and mind. Mental illness runs in my family and I recently found out my cousin was given a depression medication that I had a bad reaction to. Well, she also had a bad reaction and when she told her father about the reaction, he told her to go off of the medication because he also had a bad reaction. It's not an exact science and each individual is different; but it's something to consider when you are starting treatment.
 
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trustinhim83

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As for Abilify... I was fine yesterday, but feel sick again today. UGH! This is so frustrating.

hmmm..I wonder if it isn't just the meds mixing, and causing a weird reaction, like you had mentioned before. Didn't you say you also take meds for fibromyalgia? I think the more different meds you take the trickier it probably gets. I hope that my doc and I can find just one med that will work for me, that'd be great. Maybe I'll get to be one of the lucky ones. It seems most people I know of who are Bipolar have to take 2 to 3 different meds. all at once. Then, if you have another illness you need treatment for things get even more confusing from there.
 
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trustinhim83

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There's something else I just thought of and this is for anyone starting medications for Bipolar. I've had several doctors tell me that Bipolar is hereditary and sometimes medications that help one member of the family will help another. The same goes for medications that respond negatively with the body and mind. Mental illness runs in my family and I recently found out my cousin was given a depression medication that I had a bad reaction to. Well, she also had a bad reaction and when she told her father about the reaction, he told her to go off of the medication because he also had a bad reaction. It's not an exact science and each individual is different; but it's something to consider when you are starting treatment.

Good point. I'll bring this up with my doctor. I wish I could just go on Depakote, as I've now had two doctors tell me I need it. Plus having found out my aunt does really well on it, it would probably be a good choice. Once we are finished having kids, I'll consider it for sure.
 
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ChristianSambodhi

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hmmm..I wonder if it isn't just the meds mixing, and causing a weird reaction, like you had mentioned before. Didn't you say you also take meds for fibromyalgia? I think the more different meds you take the trickier it probably gets. I hope that my doc and I can find just one med that will work for me, that'd be great. Maybe I'll get to be one of the lucky ones. It seems most people I know of who are Bipolar have to take 2 to 3 different meds. all at once. Then, if you have another illness you need treatment for things get even more confusing from there.

Yeah, I am on Fibro meds and I think they aren't playing well together with the Abilify. I also sometimes take Xanax. Plus, right now I am having bladder spasms from my interstitial cystitis. I was on an MAOI for the interstitial cystitis; but I couldn't stick to the diet and the drugs interact with everything, even simple cold medicine. Sadly, the only drugs for interstitial cystitis are MAOIs... I think it's a mix of the bladder and the meds. I'll give it until Friday before I call my doctor and complain.
 
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BRERDO

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While I did not read through all these replies I wanted to either add or make a comment about going off meds while you are pregnant. There are plenty of options there your psychiatrist/doctor can offer while you are pregnant.

Now... I took Seroquel and it put about 15 lbs. on me and if I took it after 8pm at night, I would wake up in the morning a zombie and could not snap out of it. I have a 45 minute commute in the morning and I would literally have to pull into a rest stop about 20 miles down the highway to rest and use my phone as an alarm so I can wake up. When I got to work it was 50/50 that I would be sleeping most of the morning and I got in trouble a few times and had to explain what was going on without revealing my BiPolarness. That being said, it worked great, for what that is worth. :) I quite taking it. I am on Lamictal and Lithium now. Best of luck!
 
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