You carry between 50 and 200 mutations of your own. Do you suffer from 50 to 200 genetic diseases that your parents did not have?
Mutations are mischievously unpredictable and since we are diploids and have about 20,000 genes most mutations may be recessive.
Notice that you didn't answer my question. Do you suffer from 50 to 200 genetic diseases that your parents do not have? Yes or no?
Do the millions of base substitutions between humans and chimps cause millions of genetic diseases in humans?
That does not mean they are harmless but just recessive in the individual. The real issue is the rate of mutations; too many and the genetic load is not tolerable too few and evolution time frames are pushed way back. What is this? Another twist in the evolution fairytale
The only fairytale is your use of mutation load derived from hard selection as a limit on mutational load allowed for soft selection. Sorry, but lethal mutations are very rare. Most mutations, if they are deleterious, are only slightly deleterious.
Now how do you fit a deleterious rate of U = 4.2 into the equation. Well actually it wont fit in because now the genetic load is over 99% for humans.
That figure works fine for soft selection. At that rate, the slightly deleterious mutations fixed by genetic drift is the same as the slightly deleterious mutations eliminated through genetic drift.
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