Table 1 outlines the status of the central tenets of classical evolutionary biology in the age of evolutionary genomics and systems biology. All the classical concepts have undergone transformation, turning into much more complex, pluralistic characterizations of the evolutionary process (
15). Depicting the change in the widest strokes possible, Darwin's paramount insight on the interplay between chance and order (introduced by natural selection) survived, even if in a new, much more complex and nuanced form, with specific contributions of different types of random processes and distinct types of selection revealed.