mRNA COVID Vaccine Technology Wins 2023 Nobel Prize in Physiology or Medicine

[essentialsaltes]

Katalin Karikó and Drew Weissman win this year’s Nobel Prize in Medicine for their mRNA vaccine discoveries that made the COVID vaccines possible

Karikó and Weissman first published their seminal work on mRNA vaccines in 2005 when they worked together at the University of Pennsylvania. Their research overcame major obstacles to the use of in-vitro mRNA (synthetic) technology, such as the inflammatory response by the body that involves the production of harmful cytokines.

“What’s important here I think is that vaccines can be developed so fast, and this was as we just heard, largely due to improvements in technology and this basic discovery that allowed this,” Gunilla Karlsson-Hedestam, a member of the 2023 Nobel Committee for Physiology or Medicine, said at this morning’s announcement.

 

[jayem]

I was expecting they'd win the Nobel in 2021. The year after the Pfizer and Moderna vaccines received EUA. But--no matter when--the prize is well-deserved.

 

[Say it aint so]

SCIENCE!!

The building blocks that allowed covid vaccines to be created so fast.

 

[Aaron112]

Great ! Computer simulations that they said would be needed to be done again every six months to two years perhaps, because the computer simulated ingredients would disable a persons immune system and they would not be able to fight infections normally any more.

 

[ToddNotTodd]

SCIENCE!!

The building blocks that allowed covid vaccines to be created so fast.

The real science was the microscopic chip they put in the vaccine that somehow was powerful enough to broadcast... something... to the government. At least that's what my "good, conservative Christian" relatives think...

 

[Aaron112]

Tiny computer chips used for tracking food, tickets and other items are getting even smaller. Hitachi Ltd., a Japanese electronics maker, recently showed off radio frequency identification, or RFID, chips that are just 0.002 inches by 0.002 inches and look like bits of powder.Feb 22, 2007

Hitachi shows off world's smallest RFID chip - NBC News​

 

[ThatRobGuy]

You want to know the really funny part? Or maybe "funny" isn't the right word...maybe it's more like ironic or "tragic comedy"...

Take a look at who's name was also cited on that same research and development effort along side these other two names that won the Nobel.

Developing mRNA-vaccine technologies

mRNA vaccines combine desirable immunological properties with an outstanding safety profile and the unmet flexibility of genetic vaccines. Based on in situ protein expression, mRNA vaccines are capable of inducing a balanced immune response comprising ...

www.ncbi.nlm.nih.gov

A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs

Recent advances strongly suggest that mRNA rather than DNA will be the nucleotide basis for a new class of vaccines and drugs. Therapeutic cancer vaccines against a variety of targets have been developed on this basis and initial clinical experience suggests ...

www.ncbi.nlm.nih.gov

Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells

The design of appropriate gene delivery systems is essential for the successful application of gene therapy to clinical medicine. Cationic lipid-mediated delivery is a viable alternative to viral vector-mediated gene delivery in applications where transient ...

www.ncbi.nlm.nih.gov

Lipid Nanovectors to Deliver RNA Oligonucleotides in Cancer

The growing knowledge on the mechanisms of gene silencing and gene regulation by non-coding RNAs (ncRNA), mainly small interfering RNA (siRNA) and microRNA (miRNA), is providing a significant boost to the development of new therapeutic strategies for ...

ncbi.nlm.nih.gov

(you have to use some special search tools to find it these days)
That "R.W. Malone" name shows up quite a bit.

In a few studies published by Kariko, Malone is directly cited in the work.

I wonder if he'll get a "shout out" in that acceptance speech lol.

 

[FireDragon76]

Great ! Computer simulations that they said would be needed to be done again every six months to two years perhaps, because the computer simulated ingredients would disable a persons immune system and they would not be able to fight infections normally any more.

What are you talking about? I've had four COVID vaccine shots and my immune system is working fine.