It makes absolute sense as we are dealing with YHWH and not human reason.
Give up because God is Sovereign of His own creation? It is not a matter of giving up on what God has provided, but giving up relying on ourselves and humbly serve Him. To rest in His gift of Grace and not rely on the world and our personal idols.
What I stated is God chooses. It's everywhere in the Bible. Noah, Abraham, Moses, David and the list goes on. Hebrews 11 gives a good run down. God even chose reluctant Jonah. God did not wait to see if Saul of Tarsus was going to turn another leaf. He chose Saul, confronted him and told him he was His chosen vessel to bring the Gospel to the Gentiles (Acts 9:15).
Actually no. See above. God truly chooses and even the apostles were chosen. 11 for His Grace and one for destruction (Judas) (John 6:70-71).
God chooses and does what He pleases, showing grace to some and hardening the hearts of others (Romans 9:18).
This is a central Biblical doctrine:
Isaiah 55: NASB
8“For My thoughts are not your thoughts,
Nor are your ways My ways,” declares the LORD.
9“For as the heavens are higher than the earth,
So are My ways higher than your ways
And My thoughts than your thoughts.
10“For as the rain and the snow come down from heaven,
And do not return there without watering the earth
And making it bear and sprout,
And furnishing seed to the sower and bread to the eater;
11So will My word be which goes forth from My mouth;
It will not return to Me empty,
Without accomplishing what I desire,
And without succeeding in the matter for which I sent it.
Isaiah 45: NASB
9“Woe to the one who quarrels with his Maker—
An earthenware vessel among the vessels of earth!
Will the clay say to the potter, ‘What are you doing?’
Or the thing you are making say, ‘He has no hands’?
10“Woe to him who says to a father, ‘What are you begetting?’
Or to a woman, ‘To what are you giving birth?’”
11Thus says the LORD, the Holy One of Israel, and his Maker:
“Ask Me about the things to come concerning My sons,
And you shall commit to Me the work of My hands.
12“It is I who made the earth, and created man upon it.
I stretched out the heavens with My hands
And I ordained all their host.
13“I have aroused him in righteousness
And I will make all his ways smooth;
He will build My city and will let My exiles go free,
Without any payment or reward,” says the LORD of hosts.
Romans 9: NASB
6But it is not as though the word of God has failed. For they are not all Israel who are descended from Israel; 7nor are they all children because they are Abraham’s descendants, but: “THROUGH ISAAC YOUR DESCENDANTS WILL BE NAMED.” 8That is, it is not the children of the flesh who are children of God, but the children of the promise are regarded as descendants. 9For this is the word of promise: “AT THIS TIME I WILL COME, AND SARAH SHALL HAVE A SON.” 10And not only this, but there was Rebekah also, when she had conceived twins by one man, our father Isaac; 11for though the twins were not yet born and had not done anything good or bad, so that God’s purpose according to His choice would stand, not because of works but because of Him who calls, 12it was said to her, “THE OLDER WILL SERVE THE YOUNGER.” 13Just as it is written, “JACOB I LOVED, BUT ESAU I HATED.”
14What shall we say then? There is no injustice with God, is there? May it never be! 15For He says to Moses, “I WILL HAVE MERCY ON WHOM I HAVE MERCY, AND I WILL HAVE COMPASSION ON WHOM I HAVE COMPASSION.” 16 So then it does not depend on the man who wills or the man who runs, but on God who has mercy. 17For the Scripture says to Pharaoh, “FOR THIS VERY PURPOSE I RAISED YOU UP, TO DEMONSTRATE MY POWER IN YOU, AND THAT MY NAME MIGHT BE PROCLAIMED THROUGHOUT THE WHOLE EARTH.” 18So then He has mercy on whom He desires, and He hardens whom He desires.
19You will say to me then, “Why does He still find fault? For who resists His will?” 20 On the contrary, who are you, O man, who answers back to God? The thing molded will not say to the molder, “Why did you make me like this,” will it? 21Or does not the potter have a right over the clay, to make from the same lump one vessel for honorable use and another for common use? 22What if God, although willing to demonstrate His wrath and to make His power known, endured with much patience vessels of wrath prepared for destruction? 23And He did so to make known the riches of His glory upon vessels of mercy, which He prepared beforehand for glory, 24even us, whom He also called, not from among Jews only, but also from among Gentiles.
To coin a modern term "It ain't about us, it's about Him." Which if we are to put in more formal and reverent manner:
Soli Deo Gloria!