Cellular pathways that extend lifespan by 500 percent identified

Michael

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Pathways that extend lifespan by 500 percent identified: Discovery of cellular mechanisms could open door to more effective anti-aging therapies
The discovery of the synergistic interaction could lead to the use of combination therapies, each affecting a different pathway, to extend healthy human lifespan in the same way that combination therapies are used to treat cancer and HIV, Pankaj Kapahi, Ph.D., of the Buck Institute, has said. Kapahi is a corresponding author of the paper with Rogers and Di Chen, Ph.D., of Nanjing University.
 

Aussie Pete

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SkyWriting

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Tanj

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Yes, up to 600 years or more.

We only have about 20 years before we can add more than a year to everyone's life. More than a year, each additional year, according to the data curve.

What?
 
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SkyWriting

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That's all we need, despots, dictators, serial killers, mass murderers living decades longer. God has a reason for limiting the lifespan of mankind.
My ancestors are from Germany and Ireland according to my DNA.
 
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SkyWriting

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Every 12 months improvements in medicine add a certain amount to a current living persons lifespan.


If you graph out the data, in about 20 years it reaches more than 12 months longevity added every 12 months. That assumes no big breakthroughs on longevity.
 
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Tanj

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Every 12 months improvements in medicine add a certain amount to a current living persons lifespan.


If you graph out the data, in about 20 years it reaches more than 12 months longevity added every 12 months. That assumes no big breakthroughs on longevity.

Evidence please.
 
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Michael

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People who live by the sword would still tend to die by the sword, so I'm not all that concerned about mass murders and dictator. On the other hand, an Einstein or Newton that lived 500 years might result in technological advances on a scale that we've never seen before. Even in my lifetime science has fundamentally changed the world that I grew up in.
 
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FrumiousBandersnatch

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Every 12 months improvements in medicine add a certain amount to a current living persons lifespan.

If you graph out the data, in about 20 years it reaches more than 12 months longevity added every 12 months. That assumes no big breakthroughs on longevity.
Continuous progressions of that kind are extremely rare - diminishing returns usually cause an asymptotic tail-off; even if there are jumps or stepwise improvements, they tend to become less frequent and/or smaller over time.

The trick, for investors, is to identify where you are on the curve ;)
 
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FrumiousBandersnatch

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SkyWriting

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Continuous progressions of that kind are extremely rare - diminishing returns usually cause an asymptotic tail-off; even if there are jumps or stepwise improvements, they tend to become less frequent and/or smaller over time.The trick, for investors, is to identify where you are on the curve ;)

The opposite is happening. The abilities are compounding. Cooperation between abilities, communication, technology, Genetics, and AI are building on each other.

Remember when cars couldn't park themselves?
Remember when cell phones had shoulder straps?
Remember when DNA testing was reserved for murders?
DNA Test For Dogs - Amazon | Free 2-day Shipping w/ Prime‎
 
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FrumiousBandersnatch

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The opposite is happening. The abilities are compounding. Cooperation between abilities, communication, technology, Genetics, and AI are building on each other.

Remember when cars couldn't park themselves?
Remember when cell phones had shoulder straps?
Remember when DNA testing was reserved for murders?
DNA Test For Dogs - Amazon | Free 2-day Shipping w/ Prime‎
OK, I think we're talking at cross-purposes here. I was referring explicitly to the idea that longevity could increase in a roughly linear progression for as long as suggested in post #6.

Many technologies have been in the rapid growth phase, but each has its lifetime before it is optimised, or diminishing returns set in, or it hits a limiting factor, or it is replaced.
 
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Michael

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C. Elegans is probably not a good model for human ageing - it's more of a guide to some of the basic mechanisms that may be involved.

I agree actually. I would however expect medicine to experience the same kind of impressive breakthroughs that we've seen in electronics and other areas of research over the next century. A lot of money is being invested in the field, and it's bound to pay some impressive dividends over time.

At my age however, I'm unlikely to see the kind of advancement that would be required to see my own lifetime extended significantly as a result of such efforts.

I think I'd be better off dieting and exercising. :)
 
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