On a question and answer forum called Biology Online one poster said
"Lysosome contain enzymes that are used to break down material and get it ready for disposal. All of these enzymes work best at a low pH, reducing the risk that these enzymes will digest the very cell they are contained in should they somehow escape from the lysosome. Keep in mind that the pH of water, from which all life spring from (according to evolution) has a pH of 7. The cell could not house these enzymes without the membrane. The conundrum of getting the enzymes inside of the membrane, or the membrane around the enzymes, or the membrane evolving, then the enzyme getting on the inside, or the enzyme evolving, then the membrane around it, is a very far stretched possibility. This is so far stretched, that it is impossible.
If the enzymes develop before the membrane, the membrane would be broken down by enzymes from the outside. If the membrane evolves before the enzymes, either the membrane is already closed and is consumed by the enzyme or the enzyme develops inside the membrane, at which point would contain water instead of cell fluid. The membrane, at that point, would be consumed from the inside out because of pH."
What do some of you think? This Biologist is peculiar among many in this field in that he/she has stumbled upon one of those dilemmas (sort of paradoxical) that demonstrates the inefficiency of the hypothesis of gradual evolution (which evidence sometimes appears to support)! In other words he/she realizes one did not precede the other in development but both must have become simultaneously (just like functional DNA and the Cell). The enzymes and the membrane in a gradual model negate one another's possibility.
Since the logic is impeccable and the fact undeniable at this point, the only response I anticipate will be an attack (somehow) on the poster (either their character or doubt as to their credentials, which are not discussed). In other words since denial or defeat are not actually viable at this point scientifically, I suspect a default to dismissal (the typical approach of some EBs)....admission and realization are not acceptable, or else they face ridicule or rejection among their peer group, and could be (not will be) red flagged against publishing such an opinion.
Paul