You said that there are billions of mutations that humans have, if I understand you correctly.
Billions in the human species, yes.
But, of course, if some number of these billions are only in non-reproductive cells, these would have not a chance of passing on to make a new individual. But, of course, you never said that non-reproductive mutations could help the process of evolution.
All true, in a way. But what I was referring to regarding the 200-ish mutations that all of us have - those ARE what we get from mutations in the gametes. And since there are 7 billion or so humans alive, 7 billion times - lets say just 100 = 700,000,000,000 mutations in the human 'gene pool' (not an accurate term, I suppose - genome-pool?). I was not counting mutations in somatic (non-reproductive) cells. For example, I fully expect that by the time you are 50, you skin cells, the cells lining your intestines, etc., are probably loaded with mutations - and you are correct, those do not get passed on. But my kids, and your kids (I assume you have some) all have potentially a couple of hundred mutations you did not as an embryo.
Plus, there are many sperm cells which do have mutations, but their mutations can't be involved in producing a new individual if they are not joined to an egg to fertilize it.
That does not matter, since the 100-200 estimate is premised on each new individual. They get them somehow, sperm, egg, both.
But you are saying, if I understand you correctly, that there are many mutations which do pass on through sperm which do fertilize eggs.
Of course. But of those that do, they add up to about 100-200 per person.
Nearly all genes multitask.
But that is a pretty high level of capability, for atoms and molecules to be able to combine into DNA and to develop multi-tasking DNA, and to eventually produce us humans.
DNA is not formed de novo from atoms. Yes, ultimately all molecules are made from atoms, but things like nucleotides/nucleosides in, say, a human, are made from other nucleotides/nucleosides or are made from 'raw materials' - the Wiki has a nice (if slightly technical) description of the process
here.
RE: multi-tasking, you are anthropomorphizing, I think. While you and I may multi-task (or at least think we may), that is, engage in more than 1 task at a time - talk on the phone and drive, for example - this is not what I interpret multi-tasking in genes is.
Remember that a gene is just a sequence of DNA that performs some function - we usually think that this function is to make protein, and that is often the case. But there are genes that make RNA, and regions of DNA that to not 'make' anything but instead control the way actual genes do things - how much of a protein to make, how often, that sort of thing.
If we focus on protein coding genes, we know that in many cases, individual proteins can have different functions (or be used for different things) in different cell types, different organs, or at different times.
For example, you may have heard of the protein Collagen (ignoring for now that there are several types of collagen) - it is put into some skin-care products, used to puff-up peoples' lips for some reason, etc. But collagen also forms the matrix of bone. It is found in cartilage.
Some gene products have a role in development, but a different role later on - despite the protein being the same and expressed in the same cells.
An example of this is the gene that encodes a particular cell surface receptor for a type of growth factor. We know that these receptors have various functions in adult cells (in this case, the growth factor that these receptors bind can initiate or influence cell division, such as after an injury). But these receptors also play a role during development, and we know this due the effects we see in people that have mutations in these genes (a certain type of dwarfism is caused by a mutation in one of these growth factor receptor genes).
THAT is what I mean by 'multi-tasking' - not that a gene 'knows' it has to do this this and this today or whatever. The gene just makes the protein.
If all in existence is atoms and various sorts of physical energy, then would this not mean that non-conscious, non-intelligent stuff has produced us humans who have intelligence and consciousness, plus the ability to talk about this?
Do you believe that atoms and energies are unconscious?
You are going off on a tangent here - I am more of a 'brick and mortar' guy, this high-falutin' philosophy stuff is something I have little desire to discuss. But I am vaguely familiar with the concept of emergence, wherein (and this is a very over-simplified and probably not even very accurate way to characterize it) the 'whole' is greater then the 'sum of its parts' and this is basically just the way things work sometimes. There is a lot of material out there on this,
here is just a sampling.
Do you believe that atoms and various physical energies have had the creative ability to produce us humans who have more or less been not creative, in a number of cases?
No. Atoms are just stuff. I don't know how life as we know it came to be, and to a certain extent, I don't really care. Once life began, however, the theory of evolution explains much of what happened thereafter. Intelligent Design, creationism, etc., just offer platitudes, what ifs, just so stories - none of which are bolstered by any actual supportive evidence.
Do you believe that love comes as a product of how only physical atoms and energies have interacted?
Ultimately, probably. I see no other viable explanation. 'I just can't believe x' is not evidence against X and for Y.
Whatever you believe, I am not going to expect you to give me evidence. Because I simply don't believe physical things have the ability to prove or disprove what we think.
And yet what you
think can be altered by physical activity/inputs. Applying mild electric currents to various parts of the brain, for example, can cause a patient to experience certain memories, or to perceive certain smells, or to feel a certain way. It seems to me that if the 'mind' were extracorporeal, then such stimuli should not matter, and
Phineas Gage should have been the same old Phineas after his accident as before.
So . . . do you believe that we with our ability to talk about this, plus have the conscious experience that we do, are products of unconscious and unfeeling atoms and other energy forms which are not alive and conscious????
Ultimately, yes. And please remember that I do not have any expertise in this, nor have I done a great deal of reading on the overall topic, it just isn't my thing.
Take a single cell - say, in your liver. Is it 'alive'? Is it 'conscious'? Does it 'feel' things, psychologically? If not, then is it OK for
cells to be the product of unconscious and unfeeling atoms and other energy forms which are not alive and conscious? If not, why not?
If all in existence were produced by atoms and energies which interact according to verifiable physical principles, I would think humans would be doing better than we do, with a lot more order if we are the product of only physically orderly atoms and energies. No, I can't prove this, but what do you think, personally, if you please to say.
I think that the manner in which we live (and by we, I mean all living things) is so haphazard and in many cases absurd that to consider the possibility that we are NOT the result of mere 'dumb atoms' bouncing around is hard to take seriously.
Nature looks a lot more like nature did it than anything else, to me. But like I said, I really don't spend a lot of time on these sorts of issue, and I am fine with the notion that I simply do not have the answers to these sorts of questions.
And, no, I don't have evidence for this. This is simply something I have thought of. So, I'm asking what you think

And I am not requiring you, either, to have evidence.
Understood.
If atoms and various interacting sorts of physical energy all by themselves produced us humans with our high level of intelligence and ingenuity, I would think this could mean that atoms and various energy forms have a high level of capability; and yet humans have not demonstrated, in general, that we have such capability, plus we don't seem to have much success at understanding it all, either . . . in my opinion. And no I do not have proof or evidence of this.
You seem to be implying that in a naturalistic point of view, these atoms 'intended' to make us? That is what I get from your phrasing. If that is so, then I would have to say that in the admittedly little I know about these concepts (e.g., naturalism) I have not seen such sentiments. Quite the opposite.
So, how is it that atoms and energies so capable would produce us?????
Don't know.
Not to sound glib, but this is where I might be tempted to retort "How is it that a deity that transcends all of this - Who for no known reason, decided to create the universe - exists?" Same sort of question.
But I do understand, then, how you could ask, why has God with such capability produced us humans who live the way many of us can?
Most mutations arise as errors or replication - and replication occurs every time a cell divides.
But . . . of course . . . many such cells are not involved in producing reproductive cells. So, their mutations would be mute, in evolution, wouldn't they? And, no, you never said they would. But in case, as a general principle, cells reproducing rather often yield mutations, then this would mean that sperm producing activities can have mutations so there could be evolution < this is what I think you are saying.
I think so - I think we covered this above.
But, like I have offered, I think atoms and energies with such high capability as the only influence would produce better than us humans the way we have been doing things.
I can see your position - but let me offer an analogy -
Nails are just chunks of metal. Pointy on one end, blunt on the other. They have the amazing capability of making houses. How is it that these chunks of metal have such capabilities?
Not a great analogy, I know, but I hope it makes my point. Atoms don't have capabilities, just properties. They can bind to other atoms and produce what we call molecules. Some molecules can interact with each others to make larger structures that exhibit actions that at some point allow movement (or whatever).
Emergence, baby.... Emergence.
And how could unconscious matter and energy produce us with consciousness and contemplative abilities.
Questions that people better than me are looking into.
And how is it that they can do what is so highly intelligent, yet not make us intelligent enough to understand it?
You are presuming that it took what we call intelligence to do it. I get that position, but I do not find it very satisfactory.
I think there are people who believe that all in existence is God or some sort of conscious being. I can see they could have logic for believing this.
I can, too, in a way - or at least a deep desire for it to be so. But I hope that even such people possess this intelligence you keep referring to and at some point will realize that their opinions are not the ultimate 'placeholders' of truth, and that there are people who can address these issues (and often times with evidence on their side) better than themselves.
But a problem I can see with this is how there is very good stuff of physical creation, but humans have been making a major mess of it. So, I would think logic would indicate that not all in existence is good.
Agreed.
But is this evidence? I would say no. But I think I can look at what there is and see this, even though I can't actually prove it to someone else.
Thank you for taking the time to deal with my stuff
Hope my replies were at least relevant. I hope this does not come across as condescending or trite, but at least you seem to be actually thinking about this stuff. I cannot say the same for some others.