Umbilical cord blood test might detect Autism Spectrum Disorder

[jayem]

A Japanese study suggests that testing for a certain fatty acid metabolite in umbilical cord blood of newborns might be an indicator of autism. The specific metabolite is diHETrE--shorthand for--get ready--11,12-dihydroxyeicosatrienoic acid. It's theorized that fatty acids affect neuronal circuitry in the developing brain.

Interesting, but very speculative. And what could be done if such a test is positive?

Umbilical Cord Blood Test Could Predict Autism Risk - Neuroscience News

 

[essentialsaltes]

It might at least help with earlier detection/diagnosis/appropriate therapy. I know family members were resistant to the diagnosis despite some obvious signs; if they had known of an increased possibility, it might have led to slightly different outcomes. Not that there's a 'cure' that could have been applied.

 

[sfs]

Color me skeptical. The history of this kind of attempt at diagnostic tests is very poor. Here, they did not adequately correct for multiple hypothesis testing. I wouldn't pay any attention to the results until they've been validated in an independent sample.

 

[jayem]

When I was in active medical practice some years ago, older paternal age was thought to be an ASD risk factor. Apparently, this is still considered a possibility.

Do Older Fathers Cause Autism?