Sir Issac Newton was a nut job.
Breakdown in 1693: Around his 50th birthday, Newton suffered a severe mental breakdown, experiencing insomnia, poor digestion, and paranoia. He accused friends like John Locke and Samuel Pepys of conspiring against him.
Mercury Poisoning: Studies of his hair after his death revealed high levels of mercury, which may have resulted from his intense, secretive, and sometimes dangerous experiments with alchemy. This likely contributed to his erratic behavior and mental instability later in life.
Personality: Throughout his life, he was described as, at times, vindictive, paranoid, and quick to fly into rages when his work was questioned.