I have thought a bit about this. First thing that comes to mind is the hypocrisy of Mr Fry's assumptions:
He says this:
"How dare you create a world in which there is such misery that is not our fault"
.. then he says this:
"Because the God who created this universe, if it was created by God, is quite clearly a maniac, utter maniac. Totally selfish."
.. and yet, in 2014 1.7 Trillion dollars is known to have been spent on wars, according to figures available at Wikipedia:
https://en.wikipedia.org/wiki/List_of_countries_by_military_expenditures
I suggest actually, the ones who incite or go to war for an unjust cause, are maniacs. Maniacs of the same culture are all around us too, waging war on their neighbours in seemingly less harmful ways. For an example, I was entering the motorway with my trailer, I put my foot down, some guy merged to the onramp in the lane next to me, slightly behind my trailer. He put his foot down, tried to get in front of me. I don't drive slow, and he could not get in front before the lane merged. He had to brake (his front bumper was behind my passenger door). He got very angry about that. Pulled beside me on the motorway looking angry, actually he could have just overtaken me. That guy is a maniac too. It is not the way God or Jesus would have responded, because God is actually not a maniac. People with their ego, sense of self, greed and desire to control others, are maniacs.
Also we see that societies themselves do not leverage the maximum potential from it's citizens. We have smart, capable people who due to financial circumstances, or social stigma, are prevented from accessing that potential and making it available to the world. People with sufficient intelligence to solve the problem of cancer are stuck flipping burgers because they need to pay for the roof over their head. They eat the foods that cause cancer because that is all they can afford. If you are of the belief that bone cancer is impossible to cure, then I guess you will have a different view than I do. I think it probably is possible to cure, and I think that the reason it has not been cured yet is because insufficient investment has been made toward it at this time. Do you know how many years have gone by since Jesus Christ? Do you know the fraction of that time is responsible for hygiene and technological advancements that give us quality of life (running, hot water, frozen foods, light anywhere, transport, vacuum cleaning, sterilization). All of this happened in 7.5% of the time since Jesus (that is only significant due to being known history). The timeline stretches several times more beyond that. Imagine then, if we had have had such unimpeded research 100% of that time. Would cancer be a problem now? Imagine too, if every single dollar spent on war was spent on cancer research, or every single person who was killed in the war was tasked with solving cancer. Do you think maybe Mr Fry would have something else to argue about today?
So, when Mr Fry says “How dare you create a world in which there is such misery that is not our fault? It’s not right.", I agree that something is not right, but I rather say it is due to human negligence when we have actually been equipped sufficiently. When it is said against human misery, it is necessary to investigate what is the cause of that misery. I expect we can always find humans to blame.
It would be interesting to know whether that idea can be refuted, I think it can't.
“It’s utterly, utterly evil. Why should I respect a capricious, mean-minded, stupid God who creates a world which is so full of injustice and pain?”
This is a strawman argument, resulting from a misunderstanding of the problem, and erroneously placing the blame on the innocent person.
"We have to spend our life on our knees thanking him?! What kind of god would do that?”
I am not sure that it is demanded by God to spend our lives on our knees thanking Him. I think this is an exaggeration that Mr Fry has applied of his own accord, to emphasise his objection. It is clear that Mr Fry has found it convenient to blame God for the things he doesn't like in the world. It is common to see this happening. Can I ask you, is this the position you take too? Are you the sort of person who would expect a holy God to have made the world differently? If so, are you able to describe what should be done differently? I have asked this question to a couple of people before.