I don't think God designed them - they were simply a potential result of the fallen world bought about by man's rebellion. There would be no such thing is man had simply walked with God in the way originally intended.
How do you explain the existence of 'evil'?
You can't both claim that God designed the entire universe, and then say there are bits that he did not design.
Well actually you could, but that would involve evolution, which you've said before that you don't. Evolution doesn't actually solve this problem as God would still know what the outcome of evolution would be at the start of the universe, so it is still his design.
Further questions:
Did God know that his design of man would rebel when he was creating man? He can see the future remember.
Did God design the rule whereby diseases would come into existence if man rebelled? If not, who or what did make this rule - something more powerful than God?
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