- Dec 27, 2015
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If you show me the specific method of how the spider created the fibre in it's silk producing organ or cell; after first constructing the organ or cells to do the job; complete with spirial structure; ability to spin three or more different types of silk for specific purposed; resulting in a tensile strength greater than any man made object; and at the same developed purpose designed cutting jaws tips of the legs which don't stick to the thread; the knowledge or instinct to find an anchor point; the need and incentive to develop silk fibre in the first place; the complex chemical structure of the thread itself; all done with no "intellectual" understanding of what it was aiming for or how to do it; then I'll believe that you've got something to show me.Even if we did show you this method of trial and error, whatever that means to you, would you even acknowledge it as evidence?
But not till then.
The elaborate structure of spider silk: Structure and function of a natural high performance fiber - PMC
Biomaterials, having evolved over millions of years, often exceed man-made materials in their properties. Spider silk is one outstanding fibrous biomaterial which consists almost entirely of large proteins. Silk fibers have tensile strengths ...

On the business of "autocatalysis", it has not been shown to work in practice unless already advanced and "designed" molecules are present.

Ligating homochiral polypeptides
Ligating homochiral polypeptides cannot originate homochiral biomolecules naturalistically because the conditions this occurred in are unlikely to arise spontan
The experimenters repeatedly used the word "Design" when describing their experiments.The fascinating experiments were inspired by existing biological protein structures so cleverly designed that no one would have thought up the autocatalytic scheme without them. But ligation of E with N only occurs thanks to first converting to a highly reactive thiobenzyl ester, so the autocatalysis could not have arisen naturally. Templating merely accelerates the process by optimally moulding the reactants together. Essentially the authors demonstrated that if optically pure E and N were mixed with no contaminants present, properly activated in a laboratory, a chemical bond would form. Nothing resembling a solution to the origin of homochirality in a genetic system has been demonstrated.
In a key 1997 paper, Ghadiri and colleagues emphasized the word design multiple times when discussing these experiments and never referred to evolution. When alluding to the purpose and value of their research, they state correctly that applications in the future “would first require the ability to rationally design informational self-reproducing and self-replicating molecular systems.”
I'll believe it when I see it. In the meantime it exists in the realm of purposely designed information theory.
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