Monkeypox--leveling off

[Aldebaran]

ugh.

Of course, any mention of those who accurately predicted that this would happen will be called a conspiracy theorist.

 

[tall73]

WRAPUP 1-WHO says monkeypox 'containable' as more govts start limited vaccinations

The outbreak of monkeypox cases outside of Africa can be contained, the World Health Organization said on Tuesday, as more governments said they would launch limited vaccinations to combat rising infections of the virus.

 

[tall73]

World Health Organization monitoring 250+ monkeypox cases | KOIN.com

The World Health Organization says it is monitoring more than 250 confirmed and suspected cases.

 

[Skye1300]

This person explains monkey pox very well.

 

[tall73]

Finland discovers "highly likely" case of monkeypox

 

[DaisyDay]

ugh.

and honestly.. it's ugh for 2 reasons
#1 Obviously the children don't deserve it
#2 I can only cringe and dread how the child got it, considering the prevalence of pedos in that population.

What population? The British?

 

[Jamdoc]

What population? The British?

Homosexuals.

 

[tall73]

@sfs more updates on the sequencing.

Multi-country outbreak of Monkeypox virus: genetic divergence and first signs of microevolution

Following the (First draft genome sequence of Monkeypox virus associated with the suspected multi-country outbreak, May 2022 (confirmed case in Portugal) 111), we now release 9 additional genome sequences of Monkeypox virus causing a multi-country outbreak.

The multi-country outbreak most likely has a single origin, with all sequenced viruses released so far* tightly clustering together

We have already detected the first signs of microevolution within the outbreak cluster, namely the emergence of 7 SNPs (Table 2_2022-05-23.zip (10.9 KB)), leading to 3 descendant branches (Figure 1) including a further sub-cluster (supported by 2 SNPs) involving 2 sequences (PT0005 and PT0008). Notably, these two sequences also share a 913bp frameshift deletion in MPXV-UK_P2-010 gene coding for an Ankyrin/Host Range (Bang-D8L); D7L protein (MT903344.1 annotation). Gene loss events were already observed in the context endemic Monkeypox circulation in Central Africa, being hypothesized to correlate with human-to-human transmission (5).

This microevolution scenario also suggests that genome sequencing might provide enough resolution to track the virus dissemination in the context of the current outbreak

 

[Skye1300]

@sfs more updates on the sequencing.

Multi-country outbreak of Monkeypox virus: genetic divergence and first signs of microevolution

Following the (First draft genome sequence of Monkeypox virus associated with the suspected multi-country outbreak, May 2022 (confirmed case in Portugal) 111), we now release 9 additional genome sequences of Monkeypox virus causing a multi-country outbreak.

The multi-country outbreak most likely has a single origin, with all sequenced viruses released so far* tightly clustering together

We have already detected the first signs of microevolution within the outbreak cluster, namely the emergence of 7 SNPs (Table 2_2022-05-23.zip (10.9 KB)), leading to 3 descendant branches (Figure 1) including a further sub-cluster (supported by 2 SNPs) involving 2 sequences (PT0005 and PT0008). Notably, these two sequences also share a 913bp frameshift deletion in MPXV-UK_P2-010 gene coding for an Ankyrin/Host Range (Bang-D8L); D7L protein (MT903344.1 annotation). Gene loss events were already observed in the context endemic Monkeypox circulation in Central Africa, being hypothesized to correlate with human-to-human transmission (5).

This microevolution scenario also suggests that genome sequencing might provide enough resolution to track the virus dissemination in the context of the current outbreak

I knew it! Because all of the other cases of monkey pox before this outbreak was from people who got it from direct contact with animals. Now with this one, it's being spread person to person. Although in theory they say it was always possible to spread from person to person, it didn't. The ability to spread person to person was weak before, but now it's happening easier. Also it was never just on the genital area before, and now it is for some.

 

[sfs]

I knew it! Because all of the other cases of monkey pox before this outbreak was from people who got it from direct contact with animals.

That's false.

 

[tall73]

I knew it! Because all of the other cases of monkey pox before this outbreak was from people who got it from direct contact with animals.

Please re-read this portion:

Gene loss events were already observed in the context endemic Monkeypox circulation in Central Africa, being hypothesized to correlate with human-to-human transmission

There has been transmission human-to-human in previous outbreaks. As has been discussed, the prevalent sexual transmission, is different, likely stemming from the high risk behavior of sex venues.

What this study is indicating is that they may be able to trace the steps the virus took by the slight changes along the way. That could help them better understand how the virus is acting and why it spread internationally.

 

[tall73]

https://www.washingtonpost.com/dc-md-va/2022/05/26/monkeypox-virginia-cases-travel-vaccine/

Virginia public health officials on Thursday reported the state’s first presumed positive case of monkeypox in a Northern Virginia woman who recently traveled to an African country.

May not be related to the other cases, but I suppose still in the US

 

[tall73]

Nine monkeypox cases identified in U.S.: What we know about each of them

 

[tall73]

Coloradan believed to have monkeypox, but public risk is low

 

[Aldebaran]

Nine monkeypox cases identified in U.S.: What we know about each of them

9. Not even enough to warrant a news story.
The number of new cancer cases in the U.S. over the past week is no doubt much higher.

 

[tall73]

9. Not even enough to warrant a news story.
The number of new cancer cases in the U.S. over the past week is no doubt much higher.

It warrants a news story in that the virus has a long incubation period and they want people who have traveled to the various locations where it has been noted to be on the watch, and not engage in risky behavior which could result in further spread.

At this point, it looks likely they can control the issue, which is good. But health providers, etc. need to be aware of it, and some at high risk.

 

[tall73]

Mexico confirms first case of monkeypox

 

[Aldebaran]

Mexico confirms first case of monkeypox

No surprise there. People from dozens of other countries are going to Mexico to cross the border into the USA. Some of them are bound to bring Monkeypox with them, along with whatever else they have.

 

[Skye1300]

What concerns me is that COVID started out as a few isolated cases that everyone thought could and would be contained, then suddenly blew up and spread like wild fire.

 

[sfs]

What concerns me is that COVID started out as a few isolated cases that everyone thought could and would be contained

I don't know of any epidemiologists who thought COVID could likely be contained once there were hundreds of cases.