There are some things that most people find simply too repugnant to look at, or to have anything to do with. The same is true of God. To God, the sight of sin is absolutely repulsive.
Of Himself, Jesus Christ never sinned. He was the most perfect human being that has ever existed, or will ever exist, and He was absolutely innocent in the eyes of God. But, we must keep in mind that the entire purpose of Jesus' human life was to ultimately bear the sin, all of the sin, that has ever been committed by the billions and billions of humans that have ever lived. That, is a mind-boggling amount of sin. Why did Jesus cry out "Eloi, Eloi, Lama Sabachthani?" as His mission reached its fulfillment and He was held personally responsible for all sin? Because, with that immense load of guilt, our guilt, upon Him, for just a very few seconds, God couldn't stand the sight of Him.
Habakkuk 1:13
Thou art of purer eyes than to behold evil, and canst not look on iniquity: wherefore lookest thou upon them that deal treacherously, and holdest thy tongue when the wicked devoureth the man that is more righteous than he?