I'm not sure what translation you are using, "keep most..." or "break one of the major..." seems rather odd. One isn't commanded to keep most of the commands anymore than God telling the people of Israel they only have to keep 8 out of 10 commandments.
The commandments are rather simple:
Matt 22:37 And He said to him, “‘You shall love the Lord your God with all your heart, and with all your soul, and with all your mind.’ 38 This is the great and foremost commandment. 39 The second is like it, ‘You shall love your neighbor as yourself.’ 40 Upon these two commandments hang the whole Law and the Prophets.”
So one can try to love God with all their heart, soul, and mind as well as their neighbor as themselves, or one can repent of their sinful behavior before God (an old fashioned idea) and ask Jesus Christ to forgive them and shape them to be obedient to the two commands.
This is the summary of the commandments what the whole bible hangs on- love to God with all our heart soul and mind, love our neighbor.
How to do that is through keeping all of God's commandments.
For example, the greatest commandment to love God with all our heart, soul and mind came from the OT after Moses repeated the Ten Commandments for them to diligently keep before entering the promise land.
Deut 6:1 “Now this
is the commandment,
and these are the statutes and judgments which the Lord your God has commanded to teach you, that you may observe
them in the land which you are crossing over to possess, 2
that you may fear the Lord your God, to keep all His statutes and His commandments which I command you, you and your son and your grandson, all the days of your life, and that your days may be prolonged. 3 Therefore hear, O Israel, and [
a]be careful to observe
it, that it may be well with you, and that you may multiply greatly as the Lord God of your fathers has promised you—‘a land flowing with milk and honey.’
4 “Hear, O Israel: [
b]
The Lord our God, the Lord is one! 5 You shall love the Lord your God with all your heart, with all your soul, and with all your strength.
The greatest commandment to love our neighbor also came from the OT.
It summarizes the commandments from the Ten that deal with love to mankind
Rom 13:9 For the commandments, “You shall not commit adultery,” “You shall not murder,” “You shall not steal,” [
a]“You shall not bear false witness,” “You shall not covet,” and if
there is any other commandment, are
all summed up in this saying, namely, “You shall love your neighbor as yourself.”
On these two commandments- love to God, love to man hangs the whole Word of God. Keeping Gods commandments is love to God and man 1 John 5:2-3