There is a significant difference between a misunderstanding or disagreement in doctrinal interpretation ... and the type of anti-Christian, anti-Christ, anti-Bible hatred spewed on the internet and some "Christian" forums today. This is not coming from people who are seeking truth or open to God, Christ or Scripture, but, those whose conscience has been seared an whose heart has been hardened.
Christ did not try to reason with or persuade the hard-hearted Pharisees, but, rebuked and condemned them as "a generation of vipers" and "whitewashed tombs full of dead men's bones" (Matt 12, 23)-- Likewise, when Paul encountered this same rejection of the Gospel and God's truth among the Jews, he responded, "Your blood is on your own heads -- From now on I go to the Gentiles" (Acts 18:6). Also, in Romans 1:18-22, Paul declared, "The wrath of God is revealed from heaven .... against those who suppress the truth in their wickedness; ... they are without excuse."
Believers are to respond with gentle reason, hospitality and encouragement to all who are open to the Gospel and seeking God or even willing to hear the truth. But, to those who blatantly denigrate the Gospel, Christ and truth, we are "not to welcome them into our homes or wish them Godspeed, ... for the one who does that, participates in their evil deeds." (2 John 1:10-11)
I've written an apologetics book that offers significant verifiable proof - in addition to the Bible, that the Bible is God's inspired Word of Truth (See: UCanKnowTheTruth.Com - "You Can Know the Truth"). Science, Archaeology, Literary, Prophecy, Claims, Mathematics, etc.. While non-believers may not directly seek-out this book, it provides the ammunition believers need to contend for the faith in the face of the spirit of the antiChrist in the world today.