For Mark Kennedy - define mutation

[SLP]

as it pertains to genetics.

 

[Ceph]

Well I know I'm not Mark Kennedy, but since you seem to be incapable of using Google I'll help.

A mutation is a modification in a sequence of bases to a string of pearls, a point mutation would amount to changing the appearance of a single pearl, replacing one pearl by a pearl of another type, inserting an extra pearl, or removing a single pearl.

Mutations can be caused by external agents (UV radiation, chemical substances, etc.) or errors in DNA copying during cell division that the cell did not detect or could not fix using its DNA repair mechanisms. They can appear in the expressed part of a gene , in sequences that regulate a gene’s expression, or in other areas of DNA. Certain mutations in particular genes have no consequence for the organism thanks to redundancy in the genetic code . Others lead to changes in the structure or function of the proteins coded for by the affected genes, or even the complete suppression of protein synthesis. The genetic changes produced by mutations are transmitted from parent cells to daughter cells. If the changes occur in reproductive cells, they are transmitted from parents to offspring.

 

[Mistermystery]

Well I know I'm not Mark Kennedy,

I'm utterly dissapointed and confused

 

[Phred]

Well I know I'm not Mark Kennedy, but since you seem to be incapable of using Google I'll help.

Well.... You're obviously not capable of understanding there might be a reason a question is asked. But thanks for the dripping sarcasm. That always helps.

 

[Philosoft]

Well I know I'm not Mark Kennedy, but since you seem to be incapable of using Google I'll help.

I'm afraid you've missed the point. Ordinarily, when a member's name is used in a thread title, it's because the thread author wishes to know something about the member in question. Chances are, SLP has at least a basic knowledge of genetic mutation; his intent here is to ascertain if Mark Kennedy also has this basic knowledge. This is relevant because of previous statements on other threads made by Kennedy that call this knowledge into question.

 

[mark kennedy]

Perhaps you should specify what kind of a mutation you are refering to like, germinal, somatic, point, missense, nonsense, frameshift...or do you have another one in mind?

 

[Jet Black]

mark in getting something right for once shocker. scuse me while I phone up one of the tabloids and make a fortune.

 

[mark kennedy]

I guess if you can't get your face on the cover of the Rolling Stones the tabloids is a viable substitute.

 

[Jet Black]

they got back to me and said they would only accept the story if you were also on the moon. sorry about that.

 

[Mistermystery]

Filthy atheistical tabloits. How dare they!

 

[Loudmouth]

Perhaps you should specify what kind of a mutation you are refering to like, germinal, somatic, point, missense, nonsense, frameshift...or do you have another one in mind?

For our edification, perhaps you could tell us the difference between somatic and germinal mutations and their impact on heredity?

 

[mark kennedy]

How about my face on Mars, it does look a lot like me?

 

[mark kennedy]

For our edification, perhaps you could tell us the difference between somatic and germinal mutations and their impact on heredity?

Germinal is before the DNA replication period preceding meiosis and the somatic is before the period just prior to mitosis. In germinal the change appears in the gamete and in the somatic the change is perpetuated in the daughter cells rather then the gametes...why?

 

[Philosoft]

Germinal is before the DNA replication period preceding meiosis and the somatic is before the period just prior to mitosis.

I don't think the timing is relevant. The names simply specify which cells are involved: germinal - germ-line cells; somatic - somatic cells.

 

[mark kennedy]

I don't think the timing is relevant. The names simply specify which cells are involved: germinal - germ-line cells; somatic - somatic cells.

The timing is tied to the definition and I am unclear what you think is the point of you statement.

 

[Philosoft]

The timing is tied to the definition and I am unclear what you think is the point of you statement.

You said germinal mutations occur before DNA replication. In fact, most such mutations probably occur during replication.

 

[Loudmouth]

Germinal is before the DNA replication period preceding meiosis and the somatic is before the period just prior to mitosis. In germinal the change appears in the gamete and in the somatic the change is perpetuated in the daughter cells rather then the gametes...why?

The way I understand it is that somatic mutations happen to somatic cells, those cells that make up functional tissue. Therefore, these mutations may cause differences in the organism but are not passed on to the next generation.

Germinal mutations occur in germ line cells, those cells that are responsible for gamete production. This means that offspring may display differences due to mutations not found in the parents.

The effects of somatic and germinal mutations on the parent and offspring are quite different and important when talking about heritable mutations.

 

[mark kennedy]

The way I understand it is that somatic mutations happen to somatic cells, those cells that make up functional tissue. Therefore, these mutations may cause differences in the organism but are not passed on to the next generation.

Germinal mutations occur in germ line cells, those cells that are responsible for gamete production. This means that offspring may display differences due to mutations not found in the parents.

The effects of somatic and germinal mutations on the parent and offspring are quite different and important when talking about heritable mutations.

Of course I have no problem with this since it is well spoken and exactly what biology has found to be true. Now, what has me puzzled is why a thread bearing my name is needed to discuss these points of interest.

 

[SLP]

Well I know I'm not Mark Kennedy, but since you seem to be incapable of using Google I'll help.

I am quite capable of using Google. Apparently, you are clueless as to why I asked.

 

[SLP]

I'm afraid you've missed the point. Ordinarily, when a member's name is used in a thread title, it's because the thread author wishes to know something about the member in question. Chances are, SLP has at least a basic knowledge of genetic mutation; his intent here is to ascertain if Mark Kennedy also has this basic knowledge. This is relevant because of previous statements on other threads made by Kennedy that call this knowledge into question.

Precisely.