I am not an expert in this but with newer and more powerful particle accelerators being designed for atoms and other particles to be smashed to discover more fundimental components and trying to recreate conditions only that should of been known during the big bang - is it possible that some time in the unknown future we may accidently create a singularity/black hole in the lab or cause a tear in the space time dimension with experimenting around with such physics?
Are physists aware of how far they can go without danger?
Are physists aware of how far they can go without danger?

errr, yeah, sorry about that, our milky way galaxy's black black hole.