I'm not here for your prizes.
Bummer. I would love to see some new (especially testable) hypothesis generated and share the acclaim.

And, the first challenge is to generate a new hypothesis that can modify or challenge the theory of evolution. You are repeating some preivously done work that fits with the theory of evolution and does seem to modify our understanding of the process. If it were your work, it would be a strong contender for the modify part, which is why geneticists and biologists today revere Barbara McClintock. Good job. You appear to beleive that agents of genetic change, other than classical mutation, somehow challenge the theory of evolution. You'll have to explain your reasoning (and/or support) for this idea further.
Greg 1234 - Where? Chance and necessity as the primary source of adaptation is still being touted. Had this already been relinquished, I would have moved on to the next portion a long time ago..
David - Mutation by substitution is no longer seen as the sole source of genetic variation on which selection can act or as the sole factor in the rate at which new variation can appear. It may not even be the primary source of new variation. In general the mechanisms that have been established function randomly, although often with complex control mechanisms. Those of us who share a beleif in a God who is and has been involved in the process and who generally works in subtle ways, see appearant randomness as opportunities for God to work quietly as Christian theology predicts. A deist god would have created the process once, as anti-evolutionists claim. An absence of God could explain a non-remarkable purely random process. But, an appearantly and usually random process in which individual amino acid substitutions and other appearantly random mechanisms of change occur allows for the Christian God who is (usually subtly) and constantly involved. Recombination may be the largest source of new genotypes that selection can act on and does not require mutation. In fact eukaryotic cells have developed an amazing array of helper DNA types, whose sole job is to assist in recombination. Transposons (Jumping Genes, first described in corn by Barbara McClintock) act as a form of mutation that increase the rate at which massive (and due to their movement of complete genes more likely to be beneficial) change in genetics occur. They too are helped by dedicated DNA level mechanisms to occur. Transposons are generally thought to be responsible for the very fast levels of speciation in corn. The paper you cite, which I am very much looking forward to looking into, suggest further mechanisms of change. Wether or not they are assisted by complex molecular machinery or are a simpler mechanism makes little difference to the theory of evolution. Or, put in spiritual terms, God works in mysterious ways. I tend to think that the remarkable number of times in which the same stretch of (sometimes mechanistically very complex) DNA is used for different purpouses in wildly different organisms is evidence not only of descent from a common ancestor, but also of Gods conservation of useful DNA manuscripts for later modification and use.
Greg 1234- You would have to define evolution here. Also, you would need to state how intelligent mechanisms governing adaptation strengthens the case for random mutation. Or how its limited nature as a response to the environment strengthens microbe to man phenomena..
David- You might note that I gave the commonly accepted definition (Futuyma, etc.) for evolution in the first challenge "descent with
modification from common ancestors. Your information though interesting doesn't challenge that. Darwins contribution, put very simply is that genetic variation arises in a population and that envioronment causes speciation by acting on (selection) the available phenotypes that have arisen. It sounds like "intelligent" may be too strong a word for the mechanisms you are describing, perhaps you could use complex. Why would I need to stregthen the case for random mutation? Variation happens from a number of sources, all of which appear random. It can be selected for and against in an ongoing process. I'm curious as to what flavor of anti-evolutionist you are, knowing that might allow me to understand your arguement better. Are you claiming that there has not been enough time for more complex organisms, such as humans to be crafted from less complex ones such as microbes? Are you arguing that design must be shown or is shown? That's a tough arguement to make. As the arguements for irreducible complexity have failed, perhaps you are arguing that all of the mechanisms must be at every level simple and appearantly random mechanisms are disallowed. Do you argue the same for weather? Do you think all meetings of molecules should be non-random? Or, just the biochemical ones? You definetly should try explaining how your information or arguements modify or challenge evolution. I'm curious.
Greg 1234 - They govern the mutation. You need to clarify what you mean by affect the rate of mutation. A blast of radiation affects the rate of mutation but is not what is being referenced here. .
David- My miststatement. I blame attempting to be quick here. Some of the mechanisms are in and of themselves a from of genetic change, or in the case of transposons are analgous to a mutation. Some, such as the complex machinery that repairs many mutations do govern the mutation. Some that I mixed in here, such as genetic drift are trends that limit or effect the rate of the spread of new variants into a population of organisms, which must be accounted for when attempting to determine the speed of population change and potential speciation.
David -Many slow the rate of change, such as genetic drift and sexual selection.
Greg 1234 - We are concerned with how the change arises here, not a force acting on it subsequently.. .
David- Why? New genetic variants arise routinely. In many organisms we can predict the rate at which they will arise, including the rate at which will they arise in germ lines, which can be passed to the next generation. If you are looking for a limiting factor on evolution, wouldn't you lok at the levels at which they appear in phenotypes and populations, which is where selection can work.
Greg -
01/07/30 - ICBP 2000
The conventional view is that genetic change comes from stochastic, accidental sources: radiation, chemical, or oxidative damage, chemical instabilities in the DNA, or from inevitable errors in the replication process. However, the fact is that DNA proofreading and repair systems are remarkably effective at removing these non-biological sources of mutation. For example, consider that the E. coli cell replicates its 4.6 megabase genome every 40 minutes. That is a replication frequency of almost 2 kHz. Yet, due to the action of error-recognition and correction systems in the replication machine and in the cell to catch mistakes in already-replicated DNA, the error rate is reduced below one mistake in every 1010 base-pairs duplicated, and a similar low value is observed in mammalian cells (32). That is less than one base change in every 2000 cells, certainly well below the mutation frequencies I have measured in E. coli of about four mutations per every 100 to 1000 cells.
If by speeding up the rate of mutation you mean the adaptive mutation surfaces and fixes in less time then clarify.
David -Yep, a transposon creates more frequent appearances of variation. By the way the proceedings you reference here are interesting. Are you suggesting that DNA repair mechanisms prevent variation from occuring? Or are you suggesting that variations occur so slowly that evolution must occur more slowly? It's great to have an anti-evolutionist go beyond the "God just made it to look old, because he wants to trick us" or "It was Noahs' flood" or "evolution cause Hitler" or "God just did it and science sucks" form of arguements, which is why I am answering, but please try to present an actual arguement against evolution or better present an alternative and preferably testable hypothesis, if you'd like to make a point.