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They took blockbuster drugs for weight loss. Now their stomachs are paralyzed

ThatRobGuy

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Joanie Knight has a message for anyone considering drugs like Ozempic or Wegovy, which have become popular for the dramatic weight loss they can help people achieve.

“I wish I never touched it. I wish I’d never heard of it in my life,” said Knight, 37, from Angie, Louisiana. “This medicine made my life hell. So much hell. It has cost me money. It cost me a lot of stress, it cost me days and nights and trips with my family. It’s cost me a lot, and it’s not worth it. The price is too high.”

Brenda Allen, age 42, in Dallas, Texas, feels the same way. Her doctor prescribed Wegovy for weight loss.

Emily Wright, 38, a teacher in Toronto, Canada, started taking Ozempic in 2018. Over a year, she said she lost 80 pounds, which she’s been able to keep off. But Wright said she now vomits so frequently she had to take a leave of absence from her job.


“And even now, being off the medication for almost a year, I’m still having a lot of problems,” Allen said in an interview with CNN. She said she was at urgent care recently after vomiting so much she became dehydrated.

Doctors say more cases like these are coming to light as the popularity of the drugs soared. The US Food and Drug Administration said it has received reports of patients on the drugs experiencing stomach paralysis that sometimes has not resolved by the time it’s reported.
 

SamanthaAnastasia

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I took Chantix to quit smoking back in 2010ish. It caused me to go into psychosis when I had no previous history. That is why I try and tell people to not be the first to jump on the new medication train unless there is no other option.
 
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bèlla

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Numerous warnings were issued about the drugs in light of prominent celebrities dramatic weight loss. They said it causes problems but that didn't lessen demand. The majority prefer a quick fix over the long road. If they could take a pill and be skinny they would. Even if it harms them.

I don't know what it says about the person or our society. But it's pretty sad nonetheless.

~bella
 
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Fantine

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My husband took Ozempic briefly for severe diabetes. He lost his appetite so completely (and he is not a heavy man) that he lost 13 pounds in one month, became dehydrated, and went into stage 3 kidney disease.

He became so weakened (and he is elderly) that he is now using a walker and going to physical therapy to try to regain his strength.

The kidney specialist told us she has seen a number of other patients who had similar experiences with Ozempic.
 
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ThatRobGuy

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If they could take a pill and be skinny they would. Even if it harms them.

I don't know what it says about the person or our society. But it's pretty sad nonetheless.

That's one of the reasons why, despite the fact that I see some serious positives with regards to a single payer healthcare system, I have serious doubts as to whether or not it would play out as well here as it has in other places.

Where it's a public or private system, you need people to at least try to participate in their own health beyond 'what pill can I take to fix this so I don't have to exercise or make any sacrifices when I order in a restaurant'.

While I've often advocated for healthcare reforms and moving to single payer...I've put a partial pause in place on that for the time being given some of the things we're seeing and hearing.

I have no problem chipping in some extra tax dollars to make sure everyone can get healthcare even if they're broke. But that's a conversation that I'll go back to having once we don't have large numbers of people using diabetes drugs off-label so that they don't have to get grilled chicken instead of fried, and while there's people advocating for a "healthy at any size" movement, pretending there's nothing wrong with Lizzo's life choices and "she's perfect just the way she is", and bashing Adele and Rebel Wilson as "sellouts" for losing weight.

I have members of my own family like that...not so much in the obesity realm (though there are a few). But heart disease runs in my family. I have family members that would rather take blood pressure medication and statin drugs (despite still being in the borderline high category) in their upper 40's than make any sacrifices at meal time. "What kind of drugs can I take that will keep me alive while I continue to shovel fast food in" isn't a workable model.

I'll defer to a quote I once heard.
"For most matters of health, it's not between you and your doctor, it's between you and the waitress"
 
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bèlla

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Where it's a public or private system, you need people to at least try to participate in their own health beyond 'what pill can I take to fix this so I don't have to exercise or make any sacrifices when I order in a restaurant'.

The culture is very different here from other places. We love quick fixes and shortcuts. And we're more individualistic than most. We don't consider the impact our actions have on others. That's why recklessness doesn't have the stigma it carries elsewhere. Someone will clean up the mess. It's not our fault.

I have no problem chipping in some extra tax dollars to make sure everyone can get healthcare even if they're broke. But that's a conversation that I'll go back to having once we don't have large numbers of people using diabetes drugs off-label so that they don't have to get grilled chicken instead of fried, and while there's people advocating for a "healthy at any size" movement, pretending there's nothing wrong with Lizzo's life choices and "she's perfect just the way she is", and bashing Adele and Rebel Wilson as "sellouts" for losing weight.

We're in a period of immense enabling. While I hate to think along these lines I doubt its happenstance. The propaganda is directed to the populace but if you read between the lines you'll notice everyone doesn't follow suit.

Body positivity is a double edged sword. It's a cash cow for the pharmaceutical industry and feeds the coffers for the diet industry as well. But there's another benefit the majority won't discuss. They're keenly aware most men aren't attracted to overweight women. They may tolerate a little extra but most won't swallow 100 pounds or more. They know the more you weigh the more you'll reduce your opportunities. Which inevitably leads to less marriages and reproduction. They're also aware that morbid obesity can impact a woman's fertility and disrupt her cycle.

When they're drinking the koolaid they're not thinking about that. It works for the celebrity and they expect to have the same results but that rarely occurs. They've used a similar approach with plastic surgery. If you don't like something grab a knife and we'll photoshop the effects. But you don't see how they really look or the impact of numerous procedures. They erase it with a mouse.

The bbl phenomenon is a great example. A certain celebrity popularized the procedure which created a domino effect with the requisite maladies for good measure. Then all of a sudden she took them out but most can't do the same. Now they're stuck with boulders on their back and look like the character from Incredibles.

IMG_8705.jpeg


No one with a morsel of sense would mimic that. But I digress.

I think the movement is a hoax and wouldn't be surprised if health was factored in social credit scores. There's always an angle and we have to stop assuming they have our best interests at heart.

I have members of my own family like that...not so much in the obesity realm (though there are a few). But heart disease runs in my family. I have family members that would rather take blood pressure medication and statin drugs (despite still being in the borderline high category) in their upper 40's than make any sacrifices at meal time. "What kind of drugs can I take that will keep me alive while I continue to shovel fast food in" isn't a workable model.

I'll defer to a quote I once heard.
"For most matters of health, it's not between you and your doctor, it's between you and the waitress"

We can make it easier on ourselves by making different choices. I don't believe excess weight is healthy nor should we abuse our bodies to the point where we need a pharmaceutical cocktail to keep it running. Something has to give.

I'll be the first to admit the food industry is duplicitous. But alternatives exist and we must be willing to pursue them. I've made radical shifts in my diet. Most of the food I consume is homemade. I studied countries with different philosophies and adopted them. And ignore most of the talking heads and take few things as gospel. I know they're lying.

I don't have to be bamboozled. I could be enlightened if I want but that requires work.
~bella
 
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ThatRobGuy

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We can make it easier on ourselves by making different choices. I don't believe excess weight is healthy nor should we abuse our bodies to the point where we need a pharmaceutical cocktail to keep it running. Something has to give.

I'll be the first to admit the food industry is duplicitous. But alternatives exist and we must be willing to pursue them. I've made radical shifts in my diet. Most of the food I consume is homemade. I studied countries with different philosophies and adopted them. And ignore most of the talking heads and take few things as gospel. I know they're lying.

I don't have to be bamboozled. I could be enlightened if I want but that requires work.
Some of the "sacrifices" that could make a huge differences aren't even major sacrifices at all. But some people act like you're cutting their arm off if they can't get both cheese and bacon on their burger.

I'm not going to lie and say that I never eat pizza and fast food, or enjoy the occasional soda and ice cream.

But there's an aspect of moderation that needs to be adhered to.

I was "a tad chubby" at one point in my life...in my mid-20's, I went from having a physical job to having the IT desk job I have now and kept eating the same way. I got up to around 235 pounds (at 6' 1"). Instead of going back to Kohl's to buy bigger pants for the 3rd time in 3 years, I opted address the issue and have kept it at well under 200lbs for quite some time.

It's not major life changes. Eat the junk food less, get outside a little and move more....it's not hard.

Something as simple as "I'll have 12 oz of soda instead of getting the large plus 2 refills" or "I'll limit my fast food to 2 times a week instead 5" or "maybe I'll get broccoli instead of garlic butter mashed potatoes with my dinner" could make a big difference for a lot of people if they stuck with it for a few months.

Calories in/Calories out isn't a hard formula to follow.
 
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bèlla

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Some of the "sacrifices" that could make a huge differences aren't even major sacrifices at all. But some people act like you're cutting their arm off if they can't get both cheese and bacon on their burger.

You don't have to do it all at once. Change is a continuum. We make adjustments as we grow.

Sugar was the first thing I cut out. I discovered the dangers of refined sugars and ceased to buy them. I noticed an immediate difference in candy and soda. The sweetness was off-putting and soda was next on the list. Then candy and ice cream followed and Starbucks was the last to go.

I'll have organic sugar but I don't have more than a couple teaspoons each day. I opted for water in soda's place and set aside juice a couple of years ago. I don't mind orange juice every now and then but I'll make my own instead.

I stopped buying bread and only got it from the bakery. Eventually I reached the point where I made it myself, switched the grains and started using sourdough. That's when everything changed. Now I mill my own flour and have a pantry full of grains, legumes, nuts, dried fruits and everything I need to make whatever I want at whim.

I got rid of conveniences and forced myself to make it home. I controlled the ingredients, it tasted better and I'd eat far less. If I want a cookie I have to pull out the mixer. I make a batch and freeze the balls of dough and bake a few at a time. I don't need a bag.

I don't keep treats in my home. You'll find yourself nibbling throughout the day. I eat two to three meals and have a cup of coffee and rarely snack. I drink water around the clock and eat lots of protein, vegetables, grains and legumes, bread and fruit as desired.

I don't restrict myself calorically or eat reduced fat or light options. I prefer real food eaten seasonally. When the season passes that's it unless I preserve some for the year. I like kombucha and make my own. I have ice cream on occasion and get the fruit from the farmers market along with our vegetables.

I decided a couple of years ago that I wanted to homestead. I have some experience and I'm challenging myself to live off the land as much as possible. Things take longer to prepare but I've discovered the value of freezer meals and items on the ready for convenience sake.

It enhances our self-sufficiency while making us healthier. I make my own soaps and plan to add cheese and candles to the list. Filling the larder is satisfying. And I don't mind the work most times. That's a great impediment for excess beyond my mindset. I'd never leave the kitchen.

I don't eat that much. The ingredients are healthy and ancient grains have more nutrition than modern wheat. I burn more calories while consuming less. My body's gotten used to the food and certain things make me sick. I can handle Chipotle but that's all. I haven't eaten at a burger joint in years and no longer have Chik-Fil-A.

For the most part I follow French principles and eat like they do. That's why I'm losing weight. I don't want to carry more than necessary and put a limit on my weight and clothing size. Health and aesthetic are equal motivations for my approach. I want to look nice.

When you make up your mind it won't be swayed. I'm more feminine now if that was possible. I want to wear dresses and heels and all the things that enhance my loveliness. I'm not married yet and I think about that as well. Being physically pleasing is equally important as other qualities. I don't believe a man should have one or the other. He should have both.

~bella
 
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wing2000

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But there's an aspect of moderation that needs to be adhered to.

That's the key. It seems many can not (or will not) stop at one serving. During COVID, my wife and I started having meals in a box delivered. We lost weight without even trying...simply by not having a second portion available. And when we go out, we often will share an entree.

Sugar was the first thing I cut out. I discovered the dangers of refined sugars and ceased to buy them. I noticed an immediate difference in candy and soda. The sweetness was off-putting and soda was next on the list. Then candy and ice cream followed and Starbucks was the last to go.

The American diet is disgustingly sweet. Once one starts identifying and eliminating such foods, it becomes easier and easier to avoid them. it's been a least a decade since we had a coca cola or a doughnut in the house : )
 
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bèlla

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That's the key. It seems many can not (or will not) stop at one serving. During COVID, my wife and I started having meals in a box delivered. We lost weight without even trying...simply by not having a second portion available. And when we go out, we often will share an entree.

That's one of the reasons I don't care for buffets. There's nothing wrong with them but many act like they've never had a meal. They pile so much on their plates and a lot is wasted. It's as if they don't realize they can't eat it all beforehand.

The American diet is disgustingly sweet. Once one starts identifying and eliminating such foods, it becomes easier and easier to avoid them. it's been a least a decade since we had a coca cola or a doughnut in the house : )

I feel much better now that I've weeded everything out. I don't miss it at all.

It's good to see you. I hope you and yours are well.

~bella
 
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FireDragon76

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Another thing to consider is that diabetes itself can cause gastroparesis.

That's why these drugs are only recommended for obese people with medical complications. Given that things like high blood pressure or diabetes + obesity can have serious consequences, I'm sure the risks outweigh the benefits. But they shouldn't be used casually for just simply being overweight, there are safer options.
 
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FireDragon76

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You don't have to do it all at once. Change is a continuum. We make adjustments as we grow.

Sugar was the first thing I cut out. I discovered the dangers of refined sugars and ceased to buy them. I noticed an immediate difference in candy and soda. The sweetness was off-putting and soda was next on the list. Then candy and ice cream followed and Starbucks was the last to go.

I'll have organic sugar but I don't have more than a couple teaspoons each day. I opted for water in soda's place and set aside juice a couple of years ago. I don't mind orange juice every now and then but I'll make my own instead.

I stopped buying bread and only got it from the bakery. Eventually I reached the point where I made it myself, switched the grains and started using sourdough. That's when everything changed. Now I mill my own flour and have a pantry full of grains, legumes, nuts, dried fruits and everything I need to make whatever I want at whim.

I got rid of conveniences and forced myself to make it home. I controlled the ingredients, it tasted better and I'd eat far less. If I want a cookie I have to pull out the mixer. I make a batch and freeze the balls of dough and bake a few at a time. I don't need a bag.

I don't keep treats in my home. You'll find yourself nibbling throughout the day. I eat two to three meals and have a cup of coffee and rarely snack. I drink water around the clock and eat lots of protein, vegetables, grains and legumes, bread and fruit as desired.

I don't restrict myself calorically or eat reduced fat or light options. I prefer real food eaten seasonally. When the season passes that's it unless I preserve some for the year. I like kombucha and make my own. I have ice cream on occasion and get the fruit from the farmers market along with our vegetables.

I decided a couple of years ago that I wanted to homestead. I have some experience and I'm challenging myself to live off the land as much as possible. Things take longer to prepare but I've discovered the value of freezer meals and items on the ready for convenience sake.

It enhances our self-sufficiency while making us healthier. I make my own soaps and plan to add cheese and candles to the list. Filling the larder is satisfying. And I don't mind the work most times. That's a great impediment for excess beyond my mindset. I'd never leave the kitchen.

I don't eat that much. The ingredients are healthy and ancient grains have more nutrition than modern wheat. I burn more calories while consuming less. My body's gotten used to the food and certain things make me sick. I can handle Chipotle but that's all. I haven't eaten at a burger joint in years and no longer have Chik-Fil-A.

For the most part I follow French principles and eat like they do. That's why I'm losing weight. I don't want to carry more than necessary and put a limit on my weight and clothing size. Health and aesthetic are equal motivations for my approach. I want to look nice.

When you make up your mind it won't be swayed. I'm more feminine now if that was possible. I want to wear dresses and heels and all the things that enhance my loveliness. I'm not married yet and I think about that as well. Being physically pleasing is equally important as other qualities. I don't believe a man should have one or the other. He should have both.

~bella

Sugar in soda is just the tip of the iceberg. The phosphoric acid is terrible for bone, kidney, and dental health. One of the things worsening the epidemic of kidney disease in Central America is people drinking alot of soda because the water quality is often unsafe.

Obesity is a complicated medical condition and moralizing about it is the wrong approach. Two people can eat the same food, but one will gain weight, the other won't. There's evidence a person's microbiome makes a significant difference in how they metabolize food, among other things.
 
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ThatRobGuy

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Just here to point out that methamphetamine was marketed as “diet pills” in the 1950s.
That's where pharmaceuticals are a blessing and a curse...

While most of them have a valid clinical use, in many cases people substitute them in as a "shortcut".

Even prescription painkillers (which have caused a lot of problems recently) have a valid use for very specific circumstances.

But when you have too many people saying "my knees hurt" and the doctor says "well, your weight is part of the problem, so maybe you should drop 40lbs and see if it improves" and their reply is "nah, I'll just shop around and find a doctor that will write me the Rx for pain pills", that's a problem.

And then in some cases the pendulum swings too far the other way, and people who actually do need it get denied because doctors are trying to pull a "cover my butt" move because they're afraid they'll get in trouble for prescribing due to the past overprescribing by other doctors. I've heard more than few stories of people, post surgery, getting told they can't get "the good stuff" when that would be a time when it's actually needed. Most recently, an extended family member who got two impacted wisdom teeth surgically extracted, and the doctor wouldn't give them anything better than "take Tylenol if it gets too painful"
 
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Fantine

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Ozempic makes you lose your appetite--as it did for my very diabetic husband, with disastrous results.
It creates the willpower not to overeat that some of you achieve on your own.
I have been told that people who have used it to lose weight are advised to avoid carbs.
As I said, my husband, who was not overweight but seriously diabetic, had disastrous results--but an overweight person would have more fat reserves to deal with a rapid weight loss.
 
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bèlla

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Obesity is a complicated medical condition and moralizing about it is the wrong approach. Two people can eat the same food, but one will gain weight, the other won't. There's evidence a person's microbiome makes a significant difference in how they metabolize food, among other things.

There's numerous nuances to weight gain beyond consumption. Most people don't have identical diets, metabolisms or activity levels. Differences in brand and quality are additional factors. I've never had weight related maladies although I ate some items that weren't ideal. That's probably because I consumed more beneficial things than harmful ones.

I was never a fan of fried foods nor did I fry at home.
We used olive oil exclusively, sea salt, and a greater percentage of herbs and spices in our preparation.
I learned how to cook by watching professionals on PBS and the dishes were French or inspired by those methods. I took classes afterward to enhance my skills.
Their emphasis on quality and cultural approach to food were going to influence me eventually.

I have significantly more ingredients and tools than the average consumer and numerous resources to draw from including instruction and books numbering in the thousands. Test subjects are unlikely to procure food in the manner I do. More than 90% is purchased direct and I know the producer.

It's unlikely their commitment to self-sufficiency mirrors mine and influences their shopping habits. It's improbable they forgo convenience in difference to quality even when it costs more. And I doubt they're disciplined enough to make the things they get in jars. It's easier to grab them from a shelf.

When they're willing to grind their own meat, mill their flour, and make their own preserves, baked goods and medicines we're on the same page. When they're no longer dependent on conveniences and can whip up their own pasta, dressing and sauces at will we have something in common. When they understand the difference between good ingredients and growing methods and can detect it in the product without promoting then we're alike.

There's many doing the same and you can find them on YouTube. They may not have a chefs pantry or fancy tools but their commitment to quality is similar. They're willing to make sacrifices for better options. If that requires a garden, time in the kitchen or greater expense they'll do it.

It isn't a question of morality.. It's a question of choice and lifestyle and that begins with mindset. I didn't get here overnight. A series of decisions brought me to this point. I'm no different from the next.

Only the truth sets us free. When I walk past McDonald's I know what it is. I don't pretend because its tasty. I know it's harmful and choose not to indulge. The reward of good health is well earned. You are what you eat.

The people in those studies don't live as I do. If they did they wouldn't be there. I won't be ruled by food or spend my life under a doctors care because I wouldn't moderate my consumption or change my eating habits. That's no way to live.

I'm not downplaying the temptations or mind games perpetuated against society. They know what they're doing and where it leads. The message for the masses doesn't apply to them nor do they live that way. That's why they have trainers, nutritionists, personal chefs and practices to help them stay in shape. That's why designers don't make plus size clothes and rarely use the models. Weight is a stigma in their world and they know how to keep it off but they'll never tell you.

~bella
 
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returntosender

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Some people are ridiculous, taking anything that hasn't been proven out with testing to satisfy a need. I blame the doctors also for giving them the product outside of its original intent.
 
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durangodawood

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.....When I walk past McDonald's I know what it is. I don't pretend because its tasty. I know it's harmful and choose not to indulge. The reward of good health is well earned. You are what you eat.
......

~bella
I do think knowing the facts, as well as the habit of abstinence from that junk, actually can change our taste for it. I did a band road trip recently where by majority vote we hit a bunch of fast food - which I pretty much never eat, and almost as a novelty I figured Id participate. It felt kind of gross to be eating it, and afterward too.

I do have sympathy for people tho, because habits can be hard to shift - especially when the culture makes it so easy to stay habituated.
 
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