Something doesn’t seem right here. Take a look at this from Medline Plus:
“Androgen insensitivity syndrome (AIS) is when a person who is genetically male (who has one X and one Y chromosome) is resistant to male hormones (called androgens). As a result, the person has some of the physical traits of a woman, but the genetic makeup of a man.”
Androgen insensitivity syndrome: MedlinePlus Medical Encyclopedia
Now look at what you have posted from Accord Alliance:
“But there are girls and women who have XY chromosomes. This can happen, for example, when a girl has androgen insensitivity syndrome.”
Does having a Y chromosome make you a man? Does lacking one make you a woman? | Accord Alliance
That’s not correct. That’s a mistake. What Accord Alliance was describing is true of females with Swyer syndrome:
“In approximately 15-20 percent of patients, Swyer syndrome occurs due to mutations of the sex-determining region Y (
SRY) gene on the Y chromosome or deletion of the segment of the Y chromosome containing the
SRY gene.”
Swyer syndrome - NORD (National Organization for Rare Disorders)
This statement was correct from Accord Alliance:
“And there are boys and men who have XX chromosomes. This can happen, for example, when a gene on the Y chromosome ends up on an X chromosome, causing that X chromosome to function more like a Y.”
This is what’s known as de la Chapelle syndrome, and you can read about it here:
46,XX testicular disorder of sex development: MedlinePlus Genetics
But are you noticing something? Females with Swyer syndrome have a mutation occurring or deletion on important parts of the SRY gene. With de la Chapelle syndrome, a translocation occurs, a piece of the SRY gene attaches with an X chromosome.
But maybe it’s just a battle over words. Was Accord Alliance implying that a male with androgen insensitivity syndrome can be someone who self identifies as a girl or woman?