An interesting article on it all from a medical standpoint:
http://www.ncbi.nlm.nih.gov/pubmed/1765114?dopt=Abstract
Consanguineous unions range from cousin-cousin to more distant relatedness, and their prevalence varies by culture.
Inbreeding generally increases prereproductive mortality; crude mortality increases with inbreeding in proportion to the mortality rate.
(mortality rate = death rate)
Morbidity increases significantly with inbreeding in many diseases studies in many countries.
(it weakens the immune system)
Here is another article:
http://www.lvpei.org/resources/blindnessdue.html
Consanguinity or kinship is characterized by the sharing of common ancestors. The word is derived from the Latin consanguineus, meaning 'of common blood'. Consanguineous persons have at least one common ancestor in the preceding few generations. A consanguineous marriage is one in which two individuals related by blood, such as cousins, get married and have children.
What should consanguineous couples look out for?
- The most common defects are of the sense organs and the nervous system.
- The skin colour may be pink and the hair white.
- The eyes lack pigmentation - this is known as ocular Albinism.
- Squint in children
- Night blindness leading to Retinitis Pigmentosa
- Photophobia, decreased visual acuity, moving eye and refractive errors
Retinitis Pigmentosa is a hereditary degeneration and atrophy of the retina. It is usually progressive and leads to reduced peripheral vision that causes tunnel vision, night blindness and loss of vision. This disease affects children and young adults.
In Albinism there are defects in the pigmentation of the hair, skin and eyes. In ocular albinism, only the eyes are affected. This may be associated with photophobia (aversion to light), decreased visual acuity, nystagmus (constant jerky movement of the eyes) and refractive errors.
Anridia is a congenital condition where the iris is absent.
Coloboma of iris/choroid is the absence of either of these structures, due to developmental abnormalities.
And another:
http://www.publichealth.pitt.edu/supercourse/SupercoursePPT/17011-18001/17801.ppt#19
"Conclusion: There is a n urgent need to inform the public properly about the anticipated deleterious effects of inbreeding in societies where intermarriage widely practiced. "
(Basically, babies of inbred couples are often born premature, and end up dieing because they cannot breath.)
Epileps, high blood pressure, cancer, mental illness, heart disease, hearing deficits, and diabetes are all higher in these unions. ALL diseases were reported higher in children born of consanguineous marriages.