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Maximum Life Expectancy

Senator Cheese

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I'm hoping that there are some biologists on here that can help me with this.

As commonly documented, the average life expectancy is increasing rapidly, which is mostly attributed to a sharp decline in infant mortality, increased social health care services and a sharp decline in malnutrition in developed countries.
I remember hearing that the maximum life expectancy, however, remained untouched during these times and averages at about 120 years. That is to say that the increase in average life expectancy is not due to "everyone getting older" but due to "more people reaching ages closer to the maximum age".
Since a picture says it better than a thousand words: http://upload.wikimedia.org/wikipedia/commons/7/78/Lebenserwartung_in_D_01.svg

My questions are these:

1.) Is this true, or did I get something wrong?
2.) Is this due to the decrease in length of telomeres or are there other factors of equal or greater significance (e.g. lack of antioxidants; cellular debris, etc.)?
3.) Has there been any attempt at transfecting telomerases from one organism to another, leading to an increase in maximum life expectancy?

And, for those who want to answer:

4.) Isn't it kind of neat that the author(s) of Genesis 6:3 kind of got that number pretty straight (give or take), considering the fact that the average life expectancy of that time was well below? Sure, coincidence or perhaps even based on scientific observation - but pretty cool nonetheless..
 

PsychoSarah

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That is due to the gradual "decline" of DNA as cells divide. However, the world record for longest recorded age is 122, which exceeds the limit of 120 that is placed on humans by Yahweh (YHWH) in the bible, literally it states that humans will not have a lifespan which exceeds 120 years. And then Noah promptly breaks that rule (face palm) right after that.

Also, humans could live longer than that, especially if we learn to insert telomerase into human cells without making them cancerous, it could potentially triple our lifespan or more if the DNA decline is the primary reason humans age, and that very well could be. Will humans ever live forever? Probably not, but we could perhaps live much much longer.
 
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lesliedellow

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The greatest verified age to which anybody has ever lived was that of a French woman, who was born in 1875 and died in 1997.

Telomeres play a role in the aging process, but there are likely to be other factors at work as well. If I remember rightly, the effects of oxygen as a major cause of aging are now thought to have been overdone.
 
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Strathos

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That is due to the gradual "decline" of DNA as cells divide. However, the world record for longest recorded age is 122, which exceeds the limit of 120 that is placed on humans by Yahweh (YHWH) in the bible, literally it states that humans will not have a lifespan which exceeds 120 years. And then Noah promptly breaks that rule (face palm) right after that.

I think that passage was actually saying they had 120 more years until the flood.
 
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juvenissun

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That is due to the gradual "decline" of DNA as cells divide. However, the world record for longest recorded age is 122, which exceeds the limit of 120 that is placed on humans by Yahweh (YHWH) in the bible, literally it states that humans will not have a lifespan which exceeds 120 years. And then Noah promptly breaks that rule (face palm) right after that.

Also, humans could live longer than that, especially if we learn to insert telomerase into human cells without making them cancerous, it could potentially triple our lifespan or more if the DNA decline is the primary reason humans age, and that very well could be. Will humans ever live forever? Probably not, but we could perhaps live much much longer.

This is not related to the issue: I don't think you are 19-year old as you indicated. You are more mature than a 25-year old.
 
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juvenissun

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That is due to the gradual "decline" of DNA as cells divide. However, the world record for longest recorded age is 122, which exceeds the limit of 120 that is placed on humans by Yahweh (YHWH) in the bible, literally it states that humans will not have a lifespan which exceeds 120 years. And then Noah promptly breaks that rule (face palm) right after that.

Very good question.

Not only Noah, Biblical people lived longer than 120± until Moses.
 
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