- Mar 16, 2004
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Out of curiosity (and since this probably wouldn't come up in our debate) I've seen you assert before that rapid species change can happen but you've never put a number on that rate. Do you have one?
There is no point in trying to establish a rate at this point. My interest has been adaptive evolution for some time not just single nucleotide differences and gaps. I really don't have the energy or the patience right now to pursue it to be honest.
Also, complete human genome sequences have been made for an African, an Asian, and a cancer patient (http://news.yahoo.com/s/afp/20081105/ts_afp/healthbiotechgenome, http://science.slashdot.org/article.pl?sid=08/11/05/236212&from=rss). This article from ScienceMag (http://www.sciencemag.org/cgi/content/full/322/5903/838?) has the full lowdown but requires subscription access. A revealing paragraph:
I didn't know what to make of the others but a whole cancer genome does not impress me as being particularly helpful to Darwinism.
Bentley and colleagues sequenced the genome of a Yoruba man from Nigeria whose DNA has already been extensively studied, enabling them to check the accuracy of their technology. In the third Nature paper, Jiang Wang of the Beijing Genomics Institute in Shenzhen, China, and colleagues sequenced the genome of a Han Chinese male. The Yoruba analysis uncovered almost 4 million SNPs, including 1 million novel ones. The Chinese genome had about 3 million, including 417,000 novel SNPs. As anticipated, the African genome had greater variation per kilobase than either the Chinese or sequenced Caucasian genomes, indicative of its ancestral status.
Wonder if your model can churn out that many SNPs in six thousand years.
What makes you think it took six thousand years? These differences are most likely cyclical and if there are random mutations resulting in changes on an evolutionary scale I have yet to see any suggestion of it. His genome is still within 1 percent of your own and if they look closely at your genome and mine they would probably have similar differences.
What do I think? Not much, I have been puzzling over CVNs and other things in genomics for a while. I think it's a little early to come up with some kind of a model when these differences my not even be inheritable. Some probably are but when you are looking at evolution it makes sense to focus on adaptive evolution and by the way, it need not include random mutations.
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