[Challenged to say if he considers anything holy.]
Henry Drummond: Yes! The individual human mind. In a child's ability to master the multiplication table, there is more holiness than all your shouted hosannas and holy holies. An idea is more important that a monument and the advancement of Man's knowledge more miraculous than all the sticks turned to snakes and the parting of the waters.
Henry Drummond: Suppose God whispered into a Bertram Cate's ear that an un-Brady thought could still be holy? Must men go to jail because they find themselves at odds with a self-appointed prophet?
Matthew Harrison Brady: We must not abandon faith! Faith is the most important thing!
Henry Drummond: Then why did God plague us with the capacity to think? Mr. Brady, why do you deny the one thing that sets above the other animals? What other merit have we? The elephant is larger, the horse stronger and swifter, the butterfly more beautiful, the mosquito more prolific, even the sponge is more durable. Or does a sponge think?
Matthew Harrison Brady: I don't know. I'm a man, not a sponge!
Henry Drummond: Do you think a sponge thinks? Matthew Harrison Brady: If the Lord wishes a sponge to think, it thinks!
Henry Drummond: Does a man have the same privilege as a sponge?
Matthew Harrison Brady: Of course!
Henry Drummond: Then this man wishes to have the same privilege of a sponge, he wishes to think!
E. K. Hornbeck: Disillusionment is what little heroes are made of.
Matthew Harrison Brady: Remember the wisdom of Solomon in the book of Proverbs. "He that troubleth his own house shall inherit the wind."
E. K. Hornbeck: He that sups with the devil must have a long spoon.
Matthew Harrison Brady: But your client is wrong. He is deluded. He has lost his way.
Henry Drummond: It's a shame we don't all possess your positive knowledge of what is right and what is wrong, Mr. Brady.
Matthew Harrison Brady: I do not think about things I do not think about.
Henry Drummond: Do you ever think about things that you do think about?
Henry Drummond: The Bible is a book. It's a good book, but it is not the only book.
Henry Drummond: But all you have to do is knock on any door and say, "If you let me in, I'll live the way you want me to live, and I'll think the way you want me to think," and all the blinds'll go up and all the windows will open, and you'll never be lonely, ever again. If that's the case, I'll change the plea - that is, if you know the law's right and you're wrong.
Henry Drummond: You poor slob! You're all alone. When you go to your grave, there won't be anybody to pull the grass up over your head. Nobody to mourn you. Nobody to give a ****. You're all alone.
E. K. Hornbeck: You're wrong, Henry. You'll be there. You're the type. Who else would defend my right to be lonely?
[A crowd burns the teacher in effigy]
E. K. Hornbeck: Well, those are the boobs that make our laws. That's the democratic process.
Henry Drummond: Is that the way of things? God tells Brady what is good; to be against Brady is to be against God!
Matthew Harrison Brady: No! Every man is a free agent!
Henry Drummond: Then what is Bertram Cates doing in the Hillsboro Jail?
-Inherit the Wind (1960)
(thank you Nathan Poe for reminding me of this gem!)