Yeah, sometimes I don't know what to think on this. I know of gluten intolerant people who receive regularly without any problem, yet they can't eat a bit of bread without feeling ill. I have also heard people assert that the alcohol and the hot water "kill" the germs, but by the time the last person is communed, the water is not very warm - definitely not hot enough sanitize anything and I know priests who use very little wine in their chalice and don't seem to get sick anymore than priests that use copious amounts. So perhaps the material explanation is just that, but isn't it really a material question? Does the transcendent truth of the Eucharist defy nature even though it doesn't perceivable alter it's forms? That's really what you are saying right? The "germs" are still there, but they don't make you sick. Why not? Is it because sickness is by nature a consequence of the fall and the Eucharist by definition is a victory over the principalities and power of this world and thus render them powerless? But then there is the whole "worthily" aspect. A person could be harmed by the Eucharist if they partake unworthily, which would seem to indicate that it has more to do with the person than the Eucharist itself. But I suppose this doesn't have anything to do with "germs" - the germs could still be rendered powerless, and the "harm" could be from the incompatibility of the profane and the holy in heart. Anyway...