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It doesn’t surprise me many people with mood disorders have GI problems. That matches my experience. I guess it just makes sense.
Quite interesting.
From what I gather (and just find out in the course of living life), the role of the gut-biome is a not-at-all well understood mechanism (at present).
Oh! There’s so much to be discovered! How fascinating! The human body is definitely very interesting and a complex “machine.”
When I was in my early twenties I had stomach problems and sometimes passed blood. I was prescribed Tagamet and the doctors kept telling me I had an ulcer until I found one doctor who gave me test after test and finally ordered a colonoscopy. I had polyps in my colon the doctor said would have become cancerous if not removed. He probably saved my life. I’ve had a colonoscopy ever 5 years since then and now I’m 62That would be the simple explanation that conventional wisdom would've dictated in the past. But researchers seem to be growing more skeptical about it being just a single factor (like diet).
Why Is Early-Onset Cancer On the Rise?
As diagnoses of colorectal, breast, and other cancers continue to increase in people under age 50, researchers are trying to understand why it’s happening.www.cancer.gov
The statistics show that people born around 1990 are twice as likely to get colon cancer and four times as likely to get rectal cancer compared to those born in 1950.
Happy to hear you are healthy today! Glory to God!
Upward of 40% of us isn‘t even “human DNA”, even though we (nearly all) share versions of the same “germs” which are actually symbionts, providing an intermediary between our food and their “waste”.
A quick search on Pubmed, shows that SSRIs and other antidepressants seem to have a protective effect on colorectal cancer.
We know more than you might think:
pmc.ncbi.nlm.nih.gov
I take a 81 mg aspirin every day, studies have shown that it helps prevent colon cancerThe processed food "craze" (if we can call it that) was already well into the full swing by before 1990.
From 1970's and beyond, that's when the obesity rate started noticeably jumping up.
The article I linked before mentioned that perhaps the increase in microplastics could be a factor. However, I'm thinking that's just an preliminary inquiry on their part since it's just now gaining more attention.
I've personally wondered if perhaps overuse of antibiotics has had something to do it. Since there does appear to be at least something of an association between these cancers and disruption to the gut bacteria... Broad-spectrum antibiotics like the ones that are commonly used (and often overused) are certainly gut bacteria killers, as they go "scorched earth" on all bacteria (good or bad).
The 90's was the era where the term "antibiotic resistance" started making it into the mainstream, with the CDC having to issue warning and increased guidance. For those who remember the mid-90's awareness campaign by the CDC "Get Smart: Know When Antibiotics Work".
They did that because there were tons of people getting them prescribed when they weren't necessary.
In an NIH study reviewing prescribing patterns in the US from 2000-2010:
Despite a high probability of viral etiology, acute respiratory tract infections (ARTIs), such as bronchitis, pharyngitis and sinusitis, account for 75% of all antibiotics prescribed by office-based providers [9-11].
While I wasn't born in the 90's, but I was in elementary school and Jr. High in the 90's, and I remember those days of parents taking their kids in to get antibiotics for things like colds, sinus infections, and congestion. (despite most of those being viral, therefore, antibiotics have no impact)
There have been some smaller scale studies that have looked into and found what appears to be a large enough association that it could be causal
Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes - PubMed
Early-onset colorectal cancer (EOCRC) has been increasing worldwide. Potential risk factors may have occurred in childhood or adolescence. We investigated the associations between early-life factors and EOCRC risk, with a particular focus on long-term or recurrent antibiotic use (LRAU) and its...pubmed.ncbi.nlm.nih.gov
And the 90's was also the explosion of the usage of SSRI's in young people and prescribing rates for people under 18 skyrocketed. And interestingly enough, there is a gut connection there. Since that class of drugs targeted serotonin levels, and they now know that 90% of the body's serotonin is synthesized in the GI tract. Seems like it's a least a reasonable potential causal link to look into.
I meant about being generally unhealthy. Cancer is a dice roll. You can affect the chances but it’s never a 100% some form of cancer won’t express in your cells.
