Hey, great!
I'm sorry to say I'm not familiar with O'Loughlin. I had a quick look online and he's undoubtedly a serious scholar so I'm sure he's able to give a lot of insight, even if there are things you may not be sure about.
It's always helpful to consider what perspective the author is writing from, what kind of theological system they operate under. Even if we strive to be neutral, practically, what we believe does change how we think about things and how we interpret texts. I know this from my own life in that I think about things in a Lutheran way, in the same way a Pentecostal will think about things in a Pentecostal way, or a non-denominational will think about things in a non-denominational way etc.
So, I would be glad to be proven wrong, but I would anticipate a commentary that is at least Roman Catholic adjacent. In which case, that may show up in how he understands the Two Ways doctrine, the "sacrifice" that's mentioned in connection to the Eucharist, and the Pastoral Office, to mention a few.
Now, I know you already bought the book, so I hesitate to recommend this, but if you're looking for a good version of the Didache with less commentary, The Apostolic Fathers by Holmes is excellent! There you have a collection of the early writers, including the Didache, in good English, parallel with Greek, and with some brief but helpful introductions that don't have too many opinions or speculations.
I'd be interested to hear your thoughts on O'Loughlin's edition, though! And I'm always glad to talk about the Didache if you want to have a chat!
God bless!