I think I found my answer: (Thank you Harvest ministries)
This satisfaction comes from believing in Jesus Christ who gives us the Holy Spirit to dwell inside us (verse 39). But how exactly does the Holy Spirit satisfy? Here are just a few ways:
The Holy Spirit will transform you and make you a new creation, causing old sins, addictions, attitudes, desires, and pursuits to pass away and all things to become new. (see 2 Corinthians 5:17).
The Holy Spirit will give you the strength to live a holy life. And a holy life is a happy life. Sin is the root of all evil, destruction, pain, and sorrow in your life.
The Holy Spirit will give you the ability to understand spiritual things and to understand God's Word (see 1 Corinthians 2:14). His Word will help you mature as a Christian and will guide your path, resulting in blessing and joy.
The Holy Spirit assures you that you belong to Christ and that you will enter heaven when you die (see Romans 8:16-17, Ephesians 1:13-14). This gives comfort and peace that you can't experience apart from a relationship with God.
Jesus alone can satisfy the thirsty soul. Anyone who believes in Him will receive the Holy Spirit, who will quench their inner thirst, bringing refreshment, satisfaction, and contentment forevermore!
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Thank you Godlife ministries:
Do It All in the Power of the Spirit
Read the beginning of Acts 1:8 again: “But you will receive power when the Holy Spirit has come upon you . . .” Note that we don’t have to rely on our own power, but on God, through the power of the Holy Spirit, as you read about in Part 2 of Look to Jesus.
Jesus also taught this when he sent out the disciples, saying, “The Holy Spirit will teach you in that very hour what you ought to say” (Luke 12:11-12)
Help Others Look To Jesus
In the power of the Holy Spirit, tell your story, tell God’s story, and leave the results to God. Not everyone will decide to follow Christ. Our job is just to share the Good News, and God will take care of the rest.