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UK starts COVID human challenge studies
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<blockquote data-quote="ThatRobGuy" data-source="post: 75437270" data-attributes="member: 123415"><p>I saw an article about this earlier...</p><p></p><p>Based on what I read, they're using 18-30 (or maybe it was 18-35?) fully healthy young adults, with no pre-existing conditions.</p><p></p><p>So, statistically speaking, the group they're testing with would only have a tiny fraction of a fraction of a fraction of a chance of having some sort of severe outcome if exposed to the virus and the vaccine ended up not working.</p><p></p><p>Obviously there would be major ethical concerns with conducting a trial like that using a 65 year old with diabetes and a lung condition given what we know about it.</p><p></p><p>So I don't see anything wrong with the proposed study.</p><p></p><p>18-35 healthy people with no preexisting conditions are at a very very low risk of anything dire happening...</p><p></p><p>If a healthy 22 year old wants to take the risk of a low grade fever, stuffy nose, and cough for three to five days in the interest of speeding up a safe effective vaccine for everyone else (who may not be so lucky in terms of age and overall health)</p><p></p><p>...I say we thank their for their altruism, and let the study move forward.</p><p></p><p>When it comes to clinical trials, they're very choosy in terms of who they'll accept to minimize all potential risk.</p><p></p><p>I actually volunteered to participate in a clinical trial Cleveland clinic was conducting where they were looking for people who had tested positive on an antibody test.</p><p></p><p>Submitted my info, the two positive antibody test results from two different labs, the results of a physical (with full lipid and blood sugar panel taken within the last 120 days), etc...</p><p></p><p>Got shot down because on the questionnaire, it asked about family health history, and I have 2 grandparents who had heart attacks, and diabetes runs on my mom's side of the family.</p><p></p><p>So even though I'm a healthy 36 year old (active, good body weight, blood work came back great, liver function, the whole nine yards), got weeded out due to family health history.</p><p></p><p>So reputable medical institutions aren't going to just be trying this stuff out on people willy nilly. They're going to be trying to mitigate as much severe risk as humanly possible.</p></blockquote><p></p>
[QUOTE="ThatRobGuy, post: 75437270, member: 123415"] I saw an article about this earlier... Based on what I read, they're using 18-30 (or maybe it was 18-35?) fully healthy young adults, with no pre-existing conditions. So, statistically speaking, the group they're testing with would only have a tiny fraction of a fraction of a fraction of a chance of having some sort of severe outcome if exposed to the virus and the vaccine ended up not working. Obviously there would be major ethical concerns with conducting a trial like that using a 65 year old with diabetes and a lung condition given what we know about it. So I don't see anything wrong with the proposed study. 18-35 healthy people with no preexisting conditions are at a very very low risk of anything dire happening... If a healthy 22 year old wants to take the risk of a low grade fever, stuffy nose, and cough for three to five days in the interest of speeding up a safe effective vaccine for everyone else (who may not be so lucky in terms of age and overall health) ...I say we thank their for their altruism, and let the study move forward. When it comes to clinical trials, they're very choosy in terms of who they'll accept to minimize all potential risk. I actually volunteered to participate in a clinical trial Cleveland clinic was conducting where they were looking for people who had tested positive on an antibody test. Submitted my info, the two positive antibody test results from two different labs, the results of a physical (with full lipid and blood sugar panel taken within the last 120 days), etc... Got shot down because on the questionnaire, it asked about family health history, and I have 2 grandparents who had heart attacks, and diabetes runs on my mom's side of the family. So even though I'm a healthy 36 year old (active, good body weight, blood work came back great, liver function, the whole nine yards), got weeded out due to family health history. So reputable medical institutions aren't going to just be trying this stuff out on people willy nilly. They're going to be trying to mitigate as much severe risk as humanly possible. [/QUOTE]
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