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Absolutely no comparison.
Scrubs is witty, intelligent, fast-paced, and manages to balance humor with drama without awkward transitions. Plus, the characters are well developed, which makes you actually care about each one for different reasons.
House, on the other hand, is a mediocre show with mediocre characters speaking mediocre dialogue written in a formulaic style that may be fun once or twice, but gets boring and predictable quickly.
House is almost as bad as Grey's Anatomy - and I mean that in the worst way possible.