Thus the name, Casull doctrine no doubt? ;)
Hmmm ... The .454 Casull is one of the most powerful handgun cartridges in production. It can deliver a 250 grain (16 g) bullet with a muzzle velocity of over 1,900 feet per second (580 m/s), developing more than 2,000 ft-lb (2.7 kJ) of energy...